⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4106728 | 0.80 | — | — | |
| SCHEMBL8509963 | 0.78 | MEN1 (0.32) | — | |
| SCHEMBL9053026 | 0.76 | MEN1 (0.55) | — | |
| SCHEMBL11036436 | 0.76 | MEN1 (0.55) | — | |
| SCHEMBL525624 | 0.76 | MEN1 (0.55) | — | |
| SCHEMBL4107336 | 0.76 | MEN1 (0.55) | — | |
| SCHEMBL75556 | 0.75 | TSHR (0.56) | — | |
| SCHEMBL2337685 | 0.75 | — | — | |
| SCHEMBL1148915 | 0.74 | TSHR (0.56) | — | |
| SCHEMBL787874 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3755696-A1 | 5-HETEROARYL SUBSTITUTED INDAZOLE-3-CARBOXAMIDES AND PREPARATION AND USE THEREOF | Samumed, LLC (US) | 2020-12-30 | — | — | EP | disclosed |
| WO-2019165192-A1 | 5-HETEROARYL SUBSTITUTED INDAZOLE-3-CARBOXAMIDES AND PREPARATION AND USE THEREOF | SAMUMED, LLC (US) | 2019-08-29 | — | — | WO | disclosed |
| EP-3119393-A1 | 5-SUBSTITUTED INDAZOLE-3-CARBOXAMIDES AND PREPARATION AND USE THEREOF | Samumed, LLC (US) | 2017-01-25 | — | — | EP | disclosed |
| EP-2989096-A1 | SUBSTITUTED5-(3,5-DIMETHYLISOXAZOL-4-YL)INDOLINE-2-ONES | BeiGene, Ltd. (KY) | 2016-03-02 | — | — | EP | disclosed |
| WO-2015143380-A1 | 5-SUBSTITUTED INDAZOLE-3-CARBOXAMIDES AND PREPARATION AND USE THEREOF | SAMUMED, LLC (US) | 2015-09-24 | — | — | WO | disclosed |
| WO-2014173241-A1 | SUBSTITUTED5-(3,5-DIMETHYLISOXAZOL-4-YL)INDOLINE-2-ONES | BEIGENE, LTD. (GB) | 2014-10-30 | — | — | WO | disclosed |
| EP-2661268-A2 | INHIBITORS OF POLO-LIKE KINASE | Elan Pharmaceuticals Inc. (US) | 2013-11-13 | — | — | EP | disclosed |
| WO-2013130660-A1 | AMIDES AS PIM INHIBITORS | AMGEN INC. (US) | 2013-09-06 | — | — | WO | disclosed |
| EP-2516441-A1 | PTERIDINONES AS INHIBITORS OF POLO-LIKE KINASE | Elan Pharmaceuticals Inc. (US) | 2012-10-31 | — | — | EP | disclosed |
| WO-2012048129-A2 | INHIBITORS OF POLO-LIKE KINASE | ELAN PHARMACEUTICALS, INC. (US) | 2012-04-12 | — | — | WO | disclosed |
| US-20020019569-A1 | Oxime compounds, their use, and intermediates for their production | SUMITOMO CHEMICAL COMPANY, LIMITED | 2002-02-14 | — | — | US | disclosed |
| US-6171733-B1 | BLEND OF ALKALI SOLUBLE PHENOLIC RESIN, ACID-CROSSLINKABLE METHYLOLATED MELAMINE, PHOTOACID GENERATOR, (POLY)OXYALKYLATED ALKANOLAMINE DISPERSANT AND BLACK PIGMENT; RESOLUTION, DISPLAY CONTRAST, COLOR FILTERS | FUJIFILM OLIN CO., LTD. (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-0975586-A2 | OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION | Sumitomo Chemical Company, Limited (JP) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998045254-A2 | OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-10-15 | — | — | WO | disclosed |
| US-5691101-A | NONTOXIC PHOTORESISTS FOR MANUFACTURE OF CATHODE RAY TUBES AND IMAGE PICKUP DEVICES, ACID GENERATING COMPOUND WHICH CATALYZES CROSSLINKING OR DECOMPOSITION OF RESIN | KABUSHIKI KAISHA TOSHIBA (JP) | 1997-11-25 | — | — | US | disclosed |
| EP-0217101-A1 | Substituted diphenyl ethers, process for their preparation and their use as herbicides | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-04-08 | — | — | EP | disclosed |
| US-4113497-A | COMPOSITIONS WITH ORGANOHALOGEN COMPOUND AND DIAZONIUM SALTS AS PHOTOINITIATORS OF EPOXY COMPOUNDS IN PHOTO-POLYMERIZATION | AMERICAN CAN COMPANY (US) | 1978-09-12 | — | — | US | disclosed |
| US-3988152-A | Epoxy resin photoresist with iodoform and bismuth triphenyl | AMERICAN CAN COMPANY (US) | 1976-10-26 | — | — | US | disclosed |
| US-3977878-A | Epoxy resin photoresist with iodoform and bismuth triphenyl | AMERICAN CAN COMPANY (US) | 1976-08-31 | — | — | US | disclosed |
| US-3977874-A | CATIONIC CATALYST, PHOTOPOLYMERIZATION | AMERICAN CAN COMPANY (US) | 1976-08-31 | — | — | US | disclosed |