Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PREP | P48147 | 2/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | CPB1 | P15086 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.41 |
| ▸ | TLR4 | O00206 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5256547 | 0.91 | ALDH1A1 (0.48) | ALDH1A1GAACTSLCTSBCTSK | |
| SCHEMBL5185346 | 0.90 | CPB1 (0.49) | ALDH1A1GAACTSLCTSBCTSK | |
| SCHEMBL5185353 | 0.90 | CPB1 (0.49) | ALDH1A1GAACTSLCTSBCTSK | |
| SCHEMBL5185361 | 0.90 | CPB1 (0.49) | ALDH1A1GAACTSLCTSBCTSK | |
| SCHEMBL5254943 | 0.82 | NPC1 (0.38) | ALDH1A1GAA | |
| SCHEMBL5187939 | 0.81 | CPB1 (0.50) | ALDH1A1GAACTSLCTSBCTSK | |
| SCHEMBL5187929 | 0.81 | CPB1 (0.50) | ALDH1A1GAACTSLCTSBCTSK | |
| SCHEMBL5187949 | 0.81 | CPB1 (0.50) | ALDH1A1GAACTSLCTSBCTSK | |
| SCHEMBL14286525 | 0.77 | ALDH1A1 (0.53) | ALDH1A1GAACTSLCTSBCTSK | |
| SCHEMBL14286451 | 0.77 | ALDH1A1 (0.53) | ALDH1A1GAACTSLCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1798231-A2 | Intermediate products for the preparation of antibacterial compounds | NOVEXEL (FR) | 2007-06-20 | — | — | EP | disclosed |
| EP-1399444-B1 | NOVEL HETEROCYCLIC COMPOUNDS, METHOD FOR PREPARING SAME AND USE THEREOF AS MEDICINES, IN PARTICULAR AS ANTI-BACTERIAL AGENTS | NOVEXEL (FR) | 2007-04-11 | — | — | EP | disclosed |