SCHEMBL525805

SCHEMBL525805

CCCCCCCCCCCCON(C)C

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.48
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
CA9 Q16790 2/20 0.48
THRB P10828 2/20 0.46
MEN1 O00255 1/20 0.46
HTT P42858 1/20 0.46
KMT2A Q03164 1/20 0.46
MAPT P10636 1/20 0.46
LPAR3 Q9UBY5 6/20 0.44
LPAR2 Q9HBW0 5/20 0.44
LPAR1 Q92633 2/20 0.44
NAAA Q02083 1/20 0.44
TSHR P16473 1/20 0.44
SPHK1 Q9NYA1 1/20 0.44
DNM1 Q05193 3/20 0.43
CES2 O00748 1/20 0.43
GBA1 P04062 1/20 0.43
EPHX1 P07099 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27716434 1.00 CA12 (0.48) CA12CA1CA2CA9THRB
SCHEMBL14097235 1.00 CA12 (0.48) CA12CA1CA2CA9THRB
SCHEMBL28188990 1.00 CA12 (0.48) CA12CA1CA2CA9THRB
SCHEMBL10407022 1.00 CA12 (0.48) CA12CA1CA2CA9THRB
SCHEMBL21114427 1.00 CA12 (0.48) CA12CA1CA2CA9THRB
SCHEMBL29065831 1.00 CA12 (0.48) CA12CA1CA2CA9THRB
SCHEMBL14874595 1.00 CA12 (0.48) CA12CA1CA2CA9THRB
SCHEMBL1864784 1.00 CA12 (0.48) CA12CA1CA2CA9THRB
SCHEMBL11705765 1.00 CA12 (0.48) CA12CA1CA2CA9THRB
Bromide SCHEMBL10879596 0.97 CA12 (0.46) CA12CA1CA2CA9THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1703199-A Aggregate with enhanced deformability comprising at least three amphiphiles for improved transport through a semi-permeable barrier and use of non-invasive drugs in vivo, in particular through the skin IDEA AG (DE) 2005-11-30 CN claimed
CN-118255914-A Copolymer having carbosiloxane dendrimer structure, and composition, cosmetic raw material, film-forming agent and cosmetic containing the copolymer 陶氏东丽株式会社 2024-06-28 CN disclosed
CN-111093615-B Aqueous gelling agent-containing cleansing composition for skin or hair, aqueous gelling agent, and method for producing cleansing composition 株式会社ADEKA 2023-04-18 CN disclosed
EP-2492301-B1 NOVEL CO-MODIFIED ORGANOPOLYSILOXANE DOW TORAY CO LTD (JP) 2023-03-29 EP disclosed
CN-114949237-A Vesicle 斯昆申技术控股有限责任公司 2022-08-30 CN disclosed
CN-108137820-B Cosmetic composition, cosmetic and external preparation for skin 陶氏东丽株式会社 2022-05-27 CN disclosed
CN-113527115-A Anti-oral tumor pH sensitive intelligent material and application thereof 四川大学 2021-10-22 CN disclosed
US-20210188883-A1 HYDROPHILIC SILANES DOW TORAY CO., LTD. (JP) 2021-06-24 US disclosed
CN-106750749-B Silicon dioxide-based opening agent for polyolefin film and preparation method thereof 黄山贝诺科技有限公司 2020-11-10 CN disclosed
CN-107669564-B Skin care composition with functions of repairing and regenerating, moisturizing and delaying senescence 江少卿 2020-10-16 CN disclosed
WO-2011068250-A1 LINEAR AND CYCLIC SILOXANES AND COSMETIC COMPOSITIONS MADE THEREOF DOW CORNING TORAY CO., LTD. (JP) 2011-06-09 WO disclosed
CN-1703199-B Aggregate with enhanced deformability comprising at least three amphiphiles for improved transport through a semi-permeable barrier and use of non-invasive drugs in vivo, in particular through the skin IDEA AG 2010-04-28 CN disclosed
US-20100028391-A1 Cosmetics Comprising A Modified Organopolysiloxane DOW CORNING TORAY COMPANY, LTD. (JP) 2010-02-04 US disclosed
EP-1895979-A1 COSMETICS COMPRISING A MODIFIED ORGANOPOLYSILOXANE Dow Corning Toray Co., Ltd. (JP) 2008-03-12 EP disclosed
EP-1868657-A1 DEODORIZING COMPOSITIONS FOR BIOWAST Bioneutral Laboratories Corporation USA (US) 2007-12-26 EP disclosed
WO-2006137576-A1 COSMETICS COMPRISING A MODIFIED ORGANOPOLYSILOXANE DOW CORNING TORAY CO., LTD. (JP) 2006-12-28 WO disclosed
WO-2006137821-A1 DEODORIZING COMPOSITIONS FOR BIOWAST BIONEUTRAL LABORATORIES CORPORATION USA (US) 2006-12-28 WO disclosed
US-20060228323-A1 Compositions for treating and removing noxious materials malodors and microbes, and methods of use and preparation thereof BIONEUTRAL LABORATORIES CORPORATION USA 2006-10-12 US disclosed
CN-1703199-A Aggregate with enhanced deformability comprising at least three amphiphiles for improved transport through a semi-permeable barrier and use of non-invasive drugs in vivo, in particular through the skin IDEA AG (DE) 2005-11-30 CN disclosed
US-6258335-B1 WITH RIBULOSE 1,5-BIPHOSPHATE IN SITU CONVERSION TO 3-PHOSPHOGLYCERALDEHYDE; CONTROLLING CARBON DIOXIDE EMISSION BHATTACHARYA SANJOY KUMAR (US) 2001-07-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100028391-A1 Cosmetics Comprising A Modified Organopolysiloxane H1-0, H1-2, CHRM1 CA12 931/4885CA1 917/4885CA2 1057/4885
US-20210188883-A1 HYDROPHILIC SILANES H1-4, H1-2, ITGA4 CA12 1650/4885CA1 2117/4885CA2 1898/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.