Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 6/20 | 0.67 |
| ▸ | MAPT | P10636 | 12/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.57 |
| ▸ | RAD52 | P43351 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 7/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.51 |
| ▸ | HPGD | P15428 | 6/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4134826 | 0.85 | ADORA1 (0.74) | ADORA1MAPTALDH1A1KDM4EGAA | |
| SCHEMBL10855842 | 0.83 | ADORA1 (0.59) | ADORA1MAPTALDH1A1KDM4ERAD52 | |
| SCHEMBL970355 | 0.81 | ADORA1 (0.83) | ADORA1MAPTALDH1A1KDM4EGAA | |
| SCHEMBL8288691 | 0.81 | ADORA1 (0.68) | ADORA1MAPTALDH1A1KDM4EGAA | |
| SCHEMBL4131894 | 0.81 | ALDH1A1 (0.50) | ADORA1MAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL3499018 | 0.81 | ADORA1 (1.00) | ADORA1MAPTALDH1A1KDM4ERAD52 | |
| SCHEMBL19475110 | 0.81 | MAPT (0.72) | ADORA1MAPTALDH1A1KDM4ERAD52 | |
| SCHEMBL16007549 | 0.80 | ADORA1 (0.72) | ADORA1MAPTALDH1A1KDM4EGAA | |
| SCHEMBL10856568 | 0.79 | ADORA1 (0.69) | ADORA1MAPTALDH1A1KDM4ERAD52 | |
| SCHEMBL29229875 | 0.79 | ADORA1 (0.68) | ADORA1MAPTALDH1A1KDM4ERAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1802634-A2 | THIOPHENS AND THEIR USE AS ANTI-TUMOR AGENTS | Compass Pharmaceuticals LLC (US) | 2007-07-04 | — | — | EP | claimed |
| WO-2006044826-A2 | THIOPHENS AND THEIR USE AS ANTI-TUMOR AGENTS | COMPASS PHARMACEUTICALS LLC (US) | 2006-04-27 | — | — | WO | claimed |
| EP-1802634-A2 | THIOPHENS AND THEIR USE AS ANTI-TUMOR AGENTS | Compass Pharmaceuticals LLC (US) | 2007-07-04 | — | — | EP | disclosed |
| WO-2006044826-A2 | THIOPHENS AND THEIR USE AS ANTI-TUMOR AGENTS | COMPASS PHARMACEUTICALS LLC (US) | 2006-04-27 | — | — | WO | disclosed |