Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 11/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.67 |
| ▸ | GAA | P10253 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.64 |
| ▸ | HPGD | P15428 | 6/20 | 0.64 |
| ▸ | MEN1 | O00255 | 5/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | GLA | P06280 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL970355 | 0.90 | ADORA1 (0.83) | ADORA1MAPTKDM4EGAAALDH1A1 | |
| SCHEMBL16007549 | 0.88 | ADORA1 (0.72) | ADORA1MAPTKDM4EGAAALDH1A1 | |
| SCHEMBL352175 | 0.85 | MAPT (0.53) | ADORA1MAPTKDM4EGAAALDH1A1 | |
| SCHEMBL351992 | 0.84 | ADORA1 (0.82) | ADORA1MAPTKDM4EGAAALDH1A1 | |
| SCHEMBL10856142 | 0.82 | ADORA1 (0.72) | ADORA1MAPTKDM4EGAAALDH1A1 | |
| SCHEMBL5258265 | 0.81 | ADORA1 (0.67) | ADORA1MAPTKDM4EGAAALDH1A1 | |
| SCHEMBL938054 | 0.81 | ADORA1 (1.00) | ADORA1MAPTKDM4EGAAALDH1A1 | |
| SCHEMBL6997953 | 0.81 | ADORA1 (0.73) | ADORA1MAPTKDM4EGAAALDH1A1 | |
| SCHEMBL19475087 | 0.81 | ADORA1 (0.73) | ADORA1MAPTKDM4EGAAALDH1A1 | |
| SCHEMBL3937876 | 0.81 | ALDH1A1 (0.67) | ADORA1MAPTKDM4EGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005033102-A2 | THIOPHENE-BASED COMPOUNDS EXHIBITING ATP-UTILIZING ENZYME INHIBITORY ACTIVITY, AND COMPOSITIONS, AND USES THEREOF | AMPHORA DISCOVERY CORPORATION (US) | 2005-04-14 | — | — | WO | disclosed |