Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | FABP7 | O15540 | 1/20 | 0.49 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | STS | P08842 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19917165 | 0.92 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2NPC1RAB9ATSHR | |
| SCHEMBL17390977 | 0.90 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2NPC1RAB9ATSHR | |
| SCHEMBL17390980 | 0.90 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2NPC1RAB9ATSHR | |
| SCHEMBL9002126 | 0.90 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2NPC1RAB9ATSHR | |
| SCHEMBL17391194 | 0.90 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2NPC1RAB9ATSHR | |
| SCHEMBL15709806 | 0.86 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2NPC1RAB9ATSHR | |
| SCHEMBL15743153 | 0.86 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2NPC1RAB9ATSHR | |
| SCHEMBL15709796 | 0.86 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2NPC1RAB9ATSHR | |
| SCHEMBL280126 | 0.86 | FABP7 (0.58) | ALDH1A1SMN1; SMN2NPC1RAB9ATSHR | |
| SCHEMBL6666657 | 0.86 | FABP7 (0.58) | ALDH1A1SMN1; SMN2NPC1RAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1747206-A1 | AMINO-TETRAZOLES ANALOGUES AND METHODS OF USE | ABBOTT LABORATORIES (US) | 2007-01-31 | — | — | EP | disclosed |
| WO-2005111003-A1 | AMINO-TETRAZOLES ANALOGUES AND METHODS OF USE | ABBOTT LABORATORIES (US) | 2005-11-24 | — | — | WO | disclosed |