SCHEMBL280126

SCHEMBL280126

O=C(OCc1ccccc1)C1CC1

nearest known ligand 0.59

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
FABP7 O15540 1/20 0.58
FABP5 Q01469 1/20 0.58
ALDH1A1 P00352 5/20 0.58
GAA P10253 1/20 0.58
SMN1; SMN2 Q16637 2/20 0.55
NPC1 O15118 1/20 0.55
RAB9A P51151 1/20 0.55
TSHR P16473 2/20 0.55
L3MBTL1 Q9Y468 2/20 0.54
LMNA P02545 1/20 0.54
PKM P14618 1/20 0.54
MAPK1 P28482 1/20 0.53
SLC6A2 P23975 1/20 0.53
SLC6A3 Q01959 1/20 0.53
KMT2A Q03164 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
CYP2C19 P33261 1/20 0.53
HPGD P15428 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6666657 1.00 FABP7 (0.58) FABP7FABP5ALDH1A1GAASMN1; SMN2
SCHEMBL10917021 1.00 FABP7 (0.58) FABP7FABP5ALDH1A1GAASMN1; SMN2
Hydrochloric Acid SCHEMBL27765522 0.98 FABP7 (0.57) FABP7FABP5ALDH1A1GAASMN1; SMN2
Hydrochloric Acid SCHEMBL27944947 0.98 FABP7 (0.57) FABP7FABP5ALDH1A1GAASMN1; SMN2
SCHEMBL702762 0.95 ALDH1A1 (0.66) FABP7FABP5ALDH1A1GAASMN1; SMN2
SCHEMBL595366 0.95 ALDH1A1 (0.66) FABP7FABP5ALDH1A1GAASMN1; SMN2
SCHEMBL9982540 0.95 ALDH1A1 (0.66) FABP7FABP5ALDH1A1GAASMN1; SMN2
SCHEMBL15152701 0.93 FABP7 (0.53) FABP7FABP5ALDH1A1GAASMN1; SMN2
SCHEMBL15798022 0.93 FABP7 (0.56) FABP7FABP5ALDH1A1GAASMN1; SMN2
SCHEMBL16203189 0.93 FABP7 (0.53) FABP7FABP5ALDH1A1GAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103923765-A Detergent Composition For Process Of Manufacturing Semiconductors And Displays COWON INNOTECH INC 2014-07-16 CN claimed
CN-117813308-A Nitrogen-containing condensed ring compound, preparation method and medical application thereof 中国医药研究开发中心有限公司 2024-04-02 CN disclosed
CN-117377669-A TYK2 inhibitor and application thereof 苏多生物科学有限公司 2024-01-09 CN disclosed
CN-116981672-A Macrocyclic compounds as CFTR modulators 爱杜西亚药品有限公司 2023-10-31 CN disclosed
CN-109369635-B Compound or pharmaceutically acceptable salt thereof, application thereof and pharmaceutical composition 赛克里翁治疗有限公司 2023-06-30 CN disclosed
US-20230203071-A1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCES, INC. 2023-06-29 US disclosed
CN-109384778-B Use of a compound or a pharmaceutically acceptable salt thereof for the manufacture of a medicament for the treatment of a disease, health condition or disorder 赛克里翁治疗有限公司 2022-12-13 CN disclosed
CN-110016020-B Compound or pharmaceutically acceptable salt thereof, application and pharmaceutical composition thereof 赛克里翁治疗有限公司 2022-07-26 CN disclosed
CN-108912111-B Compounds and pharmaceutical compositions 赛克里翁治疗有限公司 2021-09-14 CN disclosed
CN-112996789-A Antiviral pyridopyrazinedione compounds 诺华股份有限公司 2021-06-18 CN disclosed
JP-2005082501-A METHOD FOR MANUFACTURING PURIFIED BENZYL ESTER COMPOUND SUMITOMO CHEMICAL CO LTD 2005-03-31 JP disclosed
EP-1517881-A1 4-(3,3-DIHALO-ALLYLOXY)PHENOXY ALKYL DERIVATIVES Syngenta Participations AG (CH) 2005-03-30 EP disclosed
CN-1186310-C Process for preparing 3,3-dimethyl-2-formoyl cyclopropane carboxylic ester SUMITOMO CHEMICAL CO (JP) 2005-01-26 CN disclosed
WO-2004002943-A1 4-(3,3-DIHALO-ALLYLOXY)PHENOXY ALKYL DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2004-01-08 WO disclosed
CN-1312244-A Process for preparing 3,3-dimethyl-2-formoyl cyclopropane carboxylic ester SUMITOMO CHEMICAL CO (JP) 2001-09-12 CN disclosed
US-5371268-A Ortho-substituted benzyl esters of cyclopropanecarboxylic acids BASF AKTIENGESELLSCHAFT (DE) 1994-12-06 US disclosed
US-5066673-A SUBSTITUTED BENZYL 2-PHENYL-1-ALK(EN)YLCYCLOPROPANE-CARBOXYLATES AND THE USE THEREOF FOR CONTROLLING PESTS BASF AKTIENGESELLSCHAFT (DE) 1991-11-19 US disclosed
US-4256907-A Preparation of substituted vinylcyclopropane-carboxylic acid esters BAYER AKTIENGESELLSCHAFT (DE) 1981-03-17 US disclosed
EP-0010154-A1 Soil insecticides containing substituted benzylcyclopropane carboxylates (I) as active compounds, preparation of these insecticides, control of soil insects by the esters (I) and substituted benzylcyclopropane carboxylates BAYER AG (DE) 1980-04-30 EP disclosed
US-4098817-A OXIDATION OF CYCLOALIPHATIC COMPOUNDS PETRO-TEX CHEMICAL CORPORATION (US) 1978-07-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230203071-A1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION HAVCR2, MAVS, CD4 FABP7 2967/4885FABP5 2315/4885ALDH1A1 1718/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.