Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.47 |
| ▸ | BHMT | Q93088 | 1/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.34 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 5/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isoleucine SCHEMBL5262337 | 0.96 | PTGS1 (0.43) | PTGS1SLC7A11BHMTSLC1A3SLC1A2 | |
| Isoleucine SCHEMBL6809072 | 0.87 | PTGS1 (0.61) | PTGS1SLC7A11SLC1A3SLC1A2SLC1A1 | |
| Isoleucine SCHEMBL10610194 | 0.87 | PTGS1 (0.61) | PTGS1SLC7A11SLC1A3SLC1A2SLC1A1 | |
| Isoleucine SCHEMBL10610189 | 0.87 | PTGS1 (0.61) | PTGS1SLC7A11SLC1A3SLC1A2SLC1A1 | |
| Isoleucine SCHEMBL3374935 | 0.81 | PTGS1 (0.53) | PTGS1SLC7A11SLC1A3SLC1A2SLC1A1 | |
| Leucine SCHEMBL2973802 | 0.80 | SLC7A5 (0.58) | PTGS1SLC7A11SLC1A3SLC1A2SLC1A1 | |
| Leucine SCHEMBL2973800 | 0.80 | SLC7A5 (0.58) | PTGS1SLC7A11SLC1A3SLC1A2SLC1A1 | |
| Serine SCHEMBL4887749 | 0.80 | PTGS1 (0.55) | PTGS1SLC7A11BHMTSLC1A3SLC1A2 | |
| Isoleucine SCHEMBL3371099 | 0.79 | PTGS1 (0.47) | PTGS1SLC7A11SLC1A3SLC1A2SLC1A1 | |
| Isoleucine SCHEMBL26918680 | 0.79 | PTGS1 (0.50) | PTGS1SLC7A11SLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1047708-B1 | PEPTIDE CHELATORS THAT PREDOMINATELY FORM A SINGLE STEREOISOMERIC SPECIES UPON COORDINATION TO A METAL CENTER | BRACCO INT BV (NL) | 2007-09-26 | — | — | EP | disclosed |
| US-6334996-B1 | RADIOLABELS FOR TARGETING SPECIFIC DIAGNOSTIC PHARMACEUTICALS | RESOLUTION PHARMACEUTICALS INC. (CA) | 2002-01-01 | — | — | US | disclosed |
| EP-1047708-A1 | PEPTIDE CHELATORS THAT PREDOMINATELY FORM A SINGLE STEREOISOMERIC SPECIES UPON COORDINATION TO A METAL CENTER | RESOLUTION PHARMACEUTICALS INC. (CA) | 2000-11-02 | — | — | EP | disclosed |
| WO-1999033863-A1 | PEPTIDE CHELATORS THAT PREDOMINATELY FORM A SINGLE STEREOISOMERIC SPECIES UPON COORDINATION TO A METAL CENTER | RESOLUTION PHARMACEUTICALS INC. (CA) | 1999-07-08 | — | — | WO | disclosed |