Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.55 |
| ▸ | BHMT | Q93088 | 1/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.34 |
| ▸ | GRM8 | O00222 | 1/20 | 0.34 |
| ▸ | GRM6 | O15303 | 1/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | GSR | P00390 | 1/20 | 0.34 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.34 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Serine SCHEMBL4851695 | 0.95 | PTGS1 (0.50) | PTGS1SLC7A11BHMTSLC1A1CYP1A2 | |
| Serine SCHEMBL1514152 | 0.91 | BHMT (0.45) | PTGS1SLC7A11BHMTSLC1A1CYP1A2 | |
| Serine SCHEMBL27873098 | 0.91 | BHMT (0.45) | PTGS1SLC7A11BHMTSLC1A1CYP1A2 | |
| Serine SCHEMBL6568302 | 0.86 | BHMT (0.41) | PTGS1SLC7A11BHMTSLC1A1CYP1A2 | |
| Serine SCHEMBL1162414 | 0.83 | PTGS1 (0.80) | PTGS1SLC7A11SLC1A1CYP1A2SLC7A5 | |
| Serine SCHEMBL1162408 | 0.83 | PTGS1 (0.80) | PTGS1SLC7A11SLC1A1CYP1A2SLC7A5 | |
| Serine SCHEMBL17113864 | 0.83 | PTGS1 (0.80) | PTGS1SLC7A11SLC1A1CYP1A2SLC7A5 | |
| Serine SCHEMBL27748272 | 0.83 | PTGS1 (0.80) | PTGS1SLC7A11SLC1A1CYP1A2SLC7A5 | |
| Serine SCHEMBL17113867 | 0.83 | PTGS1 (0.80) | PTGS1SLC7A11SLC1A1CYP1A2SLC7A5 | |
| Serine SCHEMBL26613653 | 0.83 | PTGS1 (0.80) | PTGS1SLC7A11SLC1A1CYP1A2SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5688489-A | Non-receptor mediated imaging agents | RESOLUTION PHARMACEUTICALS, INC. (CA) | 1997-11-18 | — | — | US | claimed |
| US-7320784-B1 | Immobilized labeling compounds and methods | BRACCO IMAGING S.P.A. (IT) | 2008-01-22 | — | — | US | disclosed |
| EP-1154803-B1 | IMMOBILIZED LABELING COMPOUNDS AND METHODS | BRACCO INT BV (NL) | 2004-11-17 | — | — | EP | disclosed |
| EP-1154803-A1 | IMMOBILIZED LABELING COMPOUNDS AND METHODS | Bracco International B.V. (NL) | 2001-11-21 | — | — | EP | disclosed |
| WO-2000048639-A1 | IMMOBILIZED LABELING COMPOUNDS AND METHODS | RESOLUTION PHARMACEUTICALS INC. (CA) | 2000-08-24 | — | — | WO | disclosed |