SCHEMBL5259681

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5259028	0.88	SRC (0.51)	SRCMAPTSMN1; SMN2TP53IDO1
	SCHEMBL5259745	0.87	IDO1 (0.49)	SRCMAPTSMN1; SMN2TP53IDO1
	SCHEMBL5257270	0.84	IDO1 (0.50)	SRCKMT2AMEN1IDO1SLC6A4
	SCHEMBL5261131	0.83	SRC (0.56)	SRCNOD2MAPTTP53IDO1
	SCHEMBL5257221	0.83	SRC (0.47)	SRCKMT2AMEN1IDO1SLC6A4
	SCHEMBL5261587	0.82	SRC (0.75)	SRCNOD2MAPTSMN1; SMN2KMT2A
	SCHEMBL5260988	0.81	SRC (0.74)	SRCNOD2KMT2ASLC6A4GAA
	SCHEMBL5257241	0.80	SRC (0.44)	SRCIDO1SLC6A4MGAMGAA
	SCHEMBL5260125	0.76	HTR1D (0.58)	SRCMAPTKMT2AMEN1SLC6A4
	SCHEMBL27663362	0.76	KMT2A (0.50)	SRCMAPTSMN1; SMN2TP53F7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.