Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14498781 | 0.88 | KCNH2 (0.65) | KCNH2MTNR1AMTNR1B | |
| SCHEMBL5260764 | 0.82 | SLC2A1 (0.51) | KCNH2 | |
| SCHEMBL5264690 | 0.82 | KCNH2 (0.61) | KCNH2 | |
| SCHEMBL5260522 | 0.79 | KCNH2 (0.58) | KCNH2 | |
| SCHEMBL5258829 | 0.79 | KCNH2 (0.48) | KCNH2 | |
| SCHEMBL5261624 | 0.79 | KCNH2 (0.79) | KCNH2 | |
| SCHEMBL5262816 | 0.78 | KCNH2 (0.51) | KCNH2 | |
| SCHEMBL5260199 | 0.76 | KCNH2 (0.76) | KCNH2 | |
| SCHEMBL4276734 | 0.76 | KCNH2 (0.65) | KCNH2 | |
| SCHEMBL4276747 | 0.76 | KCNH2 (0.65) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1399443-B1 | NITROGEN-CONTAINING BICYCLIC HETEROCYCLES FOR USE AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 2007-12-12 | — | — | EP | claimed |