Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 5/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.47 |
| ▸ | CCR8 | P51685 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14498803 | 0.89 | KCNH2 (0.60) | SLC2A1KCNH2CCR8 | |
| SCHEMBL5258829 | 0.87 | KCNH2 (0.48) | SLC2A1KCNH2 | |
| SCHEMBL5259762 | 0.82 | KCNH2 (0.50) | KCNH2 | |
| SCHEMBL5261624 | 0.76 | KCNH2 (0.79) | KCNH2 | |
| SCHEMBL14341200 | 0.76 | KCNH2 (0.62) | SLC2A1KCNH2 | |
| SCHEMBL5262816 | 0.75 | KCNH2 (0.51) | KCNH2 | |
| SCHEMBL5260199 | 0.75 | KCNH2 (0.76) | SLC2A1KCNH2 | |
| SCHEMBL5263226 | 0.74 | KCNH2 (0.54) | KCNH2 | |
| SCHEMBL5260170 | 0.74 | KCNH2 (0.55) | SLC2A1KCNH2 | |
| SCHEMBL5262423 | 0.74 | KCNH2 (0.59) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1399443-B1 | NITROGEN-CONTAINING BICYCLIC HETEROCYCLES FOR USE AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 2007-12-12 | — | — | EP | claimed |