Sugi Predict

Sugi Predict / Compounds / SCHEMBL5260193

SCHEMBL5260193

SCHEMBL5260193

CCOC(=O)c1cc2cc(OC)c(N)cc2[nH]1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 4/20 0.60
▸ ALDH1A1 P00352 4/20 0.60
▸ HPGD P15428 4/20 0.60
▸ RAB9A P51151 3/20 0.60
▸ NPC1 O15118 2/20 0.60
▸ LMNA P02545 2/20 0.60
▸ HTT P42858 1/20 0.60
▸ L3MBTL1 Q9Y468 1/20 0.60
▸ KMT2A Q03164 3/20 0.59
▸ SMN1; SMN2 Q16637 2/20 0.59
▸ GAA P10253 2/20 0.59
▸ MEN1 O00255 2/20 0.59
▸ GLA P06280 1/20 0.59
▸ MAPT P10636 1/20 0.59
▸ ATM Q13315 1/20 0.59
▸ HSD17B10 Q99714 1/20 0.57
▸ MMP13 P45452 8/20 0.55
▸ MMP2 P08253 6/20 0.55
▸ ALOX15 P16050 1/20 0.54
▸ HRH3 Q9Y5N1 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18332087 0.95 KDM4E (0.60) KDM4EALDH1A1HPGDRAB9ANPC1
SCHEMBL214768 0.89 KDM4E (0.66) KDM4EALDH1A1HPGDRAB9ANPC1
SCHEMBL3253190 0.86 KDM4E (0.63) KDM4EALDH1A1HPGDRAB9ANPC1
SCHEMBL8355371 0.86 XDH (0.47) KDM4EALDH1A1HPGDRAB9ANPC1
SCHEMBL7042205 0.85 ALDH1A1 (0.61) KDM4EALDH1A1HPGDRAB9ANPC1
SCHEMBL14240080 0.85 ALDH1A1 (0.43) KDM4EALDH1A1HPGDRAB9ANPC1
SCHEMBL18332191 0.85 ALDH1A1 (0.63) KDM4EALDH1A1HPGDRAB9ANPC1
SCHEMBL1397951 0.84 ALDH1A1 (0.60) KDM4EALDH1A1HPGDRAB9ANPC1
SCHEMBL5419394 0.84 KDM4E (0.60) KDM4EALDH1A1HPGDRAB9ANPC1
SCHEMBL7086766 0.84 KDM4E (0.60) KDM4EALDH1A1HPGDRAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114890999-B Preparation method of PQQ 江苏信佑生物有限公司 2023-10-24 — — CN claimed
EP-1866307-A1 SYNTHESIS OF PYRROLOQUINOLINE QUINONE (PQQ) CLF Medical Technology Acceleration Program, Inc. (US) 2007-12-19 — — EP claimed
US-20070072894-A1 Synthesis of pyrroloquinoline quinone (PQQ) CLF MEDICAL TECHNOLOGY ACCELERATION PROGRAM, INC. 2007-03-29 — — US claimed
WO-2006102642-A1 SYNTHESIS OF PYRROLOQUINOLINE QUINONE (PQQ) CLF MEDICAL TECHNOLOGY ACCELERATION PROGRAM, INC. (US) 2006-09-28 — — WO claimed
US-5938792-A APPLYING TO KERATINOUS FIBERS UNDER BASIC CONDITIONS COMPOSITION COMPRISING AMINOINDOLE COUPLER, OXIDATION DYE PRECURSOR, OXIDIZING AGENT L'OREAL (FR) 1999-08-17 — — US claimed
US-5752982-A DYEING HAIR IN LIGHTFAST, WASHFAST COLORS L'OREAL (FR) 1998-05-19 — — US claimed
EP-0578735-B1 NOVEL KERATIN FIBRE DYEING METHOD USING AMINOINDOLES, WITH ACID pH, COMPOSITIONS THEREFOR AND NOVEL AMINOINDOLE COMPOUNDS OREAL (FR) 1996-01-03 — — EP claimed
EP-0580713-B1 METHOD FOR DYEING KERATIN FIBRES WITH AMINOINDOLES HAVING ALKALINE pH, AND COMPOSITIONS THEREFOR OREAL (FR) 1995-03-01 — — EP claimed
EP-0460996-B1 Keratinic fibres dyeing process with an aminoindol associated with a quinone derivative OREAL (FR) 1994-09-14 — — EP claimed
EP-0580713-A1 METHOD FOR DYEING KERATIN FIBRES WITH AMINOINDOLES HAVING ALKALINE pH, AND COMPOSITIONS THEREFOR. OREAL (FR) 1994-02-02 — — EP claimed
EP-0578735-A1 NOVEL KERATIN FIBRE DYEING METHOD USING AMINOINDOLES, WITH ACID pH, COMPOSITIONS THEREFOR AND NOVEL AMINOINDOLE COMPOUNDS. OREAL (FR) 1994-01-19 — — EP claimed
US-5180400-A METHOD FOR DYEING KERATINOUS FIBRES USING AN AMINOINDOLE IN COMBINATION WITH A QUINONE DERIVATIVE L'OREAL (FR) 1993-01-19 — — US claimed
WO-1992018093-A1 METHOD FOR DYEING KERATIN FIBRES WITH AMINOINDOLES HAVING ALKALINE pH, AND COMPOSITIONS THEREFOR L'OREAL (FR) 1992-10-29 — — WO claimed
WO-1992017157-A1 NOVEL KERATIN FIBRE DYEING METHOD USING AMINOINDOLES, WITH ACID pH, COMPOSITIONS THEREFOR AND NOVEL AMINOINDOLE COMPOUNDS L'OREAL (FR) 1992-10-15 — — WO claimed
EP-0460996-A1 Keratinic fibres dyeing process with an aminoindol associated with a quinone derivative L'OREAL (FR) 1991-12-11 — — EP claimed
CN-118120927-A Small-molecule collagen peptide oral liquid for resisting skin aging and preparation method and application thereof 杭州曼士元食品科技有限公司 2024-06-04 — — CN disclosed
CN-118020944-A Composition for promoting generation of I-type and III-type collagen simultaneously, application thereof and food containing composition 仙乐健康科技股份有限公司 2024-05-14 — — CN disclosed
WO-1992018093-A1 METHOD FOR DYEING KERATIN FIBRES WITH AMINOINDOLES HAVING ALKALINE pH, AND COMPOSITIONS THEREFOR L'OREAL (FR) 1992-10-29 — — WO disclosed
WO-1992017157-A1 NOVEL KERATIN FIBRE DYEING METHOD USING AMINOINDOLES, WITH ACID pH, COMPOSITIONS THEREFOR AND NOVEL AMINOINDOLE COMPOUNDS L'OREAL (FR) 1992-10-15 — — WO disclosed
EP-0460996-A1 Keratinic fibres dyeing process with an aminoindol associated with a quinone derivative L'OREAL (FR) 1991-12-11 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070072894-A1 Synthesis of pyrroloquinoline quinone (PQQ) QPCT, SYNCRIP, SFPQ KDM4E 730/4885ALDH1A1 3446/4885HPGD 109/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.