Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANO1 | Q5XXA6 | 7/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 2/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4150011 | 0.84 | MEN1 (0.52) | ANO1SMN1; SMN2MAPTTP53MEN1 | |
| SCHEMBL4147196 | 0.74 | ANO1 (0.53) | ANO1SMN1; SMN2MAPTTP53MEN1 | |
| SCHEMBL5550330 | 0.72 | HDAC1 (0.67) | ANO1MAPTTP53MEN1KMT2A | |
| SCHEMBL4135317 | 0.70 | ANO1 (0.53) | ANO1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL14366827 | 0.70 | HPGD (0.67) | SMN1; SMN2MAPTTP53MEN1HPGD | |
| SCHEMBL11097805 | 0.68 | KIF11 (0.54) | SMN1; SMN2MAPTMEN1HPGDKMT2A | |
| SCHEMBL4147246 | 0.67 | ANO1 (0.98) | ANO1SMN1; SMN2MAPTTP53 | |
| SCHEMBL4134799 | 0.67 | ANO1 (1.00) | ANO1SMN1; SMN2MAPTTP53 | |
| SCHEMBL4151223 | 0.67 | ANO1 (1.00) | ANO1SMN1; SMN2MAPTTP53 | |
| SCHEMBL4147414 | 0.65 | ANO1 (0.66) | ANO1SMN1; SMN2MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1802634-A2 | THIOPHENS AND THEIR USE AS ANTI-TUMOR AGENTS | Compass Pharmaceuticals LLC (US) | 2007-07-04 | — | — | EP | claimed |
| WO-2006044826-A2 | THIOPHENS AND THEIR USE AS ANTI-TUMOR AGENTS | COMPASS PHARMACEUTICALS LLC (US) | 2006-04-27 | — | — | WO | claimed |
| EP-1802634-A2 | THIOPHENS AND THEIR USE AS ANTI-TUMOR AGENTS | Compass Pharmaceuticals LLC (US) | 2007-07-04 | — | — | EP | disclosed |
| WO-2006044826-A2 | THIOPHENS AND THEIR USE AS ANTI-TUMOR AGENTS | COMPASS PHARMACEUTICALS LLC (US) | 2006-04-27 | — | — | WO | disclosed |