Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.67 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.67 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.67 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.67 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.66 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.66 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.66 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.66 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28530338 | 0.86 | PDK1 (0.64) | HDAC1HDAC7HDAC8HDAC6PDK1 | |
| SCHEMBL5549558 | 0.81 | CA12 (0.59) | CA12CA1CA2CA9NPC1 | |
| SCHEMBL3765919 | 0.81 | CA12 (0.59) | HDAC1HDAC7HDAC8HDAC6PDK1 | |
| SCHEMBL3549311 | 0.81 | CA12 (0.59) | CA12CA1CA2CA9NPC1 | |
| Trifluoroacetic Acid SCHEMBL5153804 | 0.80 | PDK1 (0.53) | HDAC1HDAC7HDAC8HDAC6PDK1 | |
| SCHEMBL4132599 | 0.79 | RXFP1 (0.56) | CA12CA9NPC1MEN1KMT2A | |
| SCHEMBL28883 | 0.79 | L3MBTL1 (0.79) | HDAC1HDAC7HDAC8HDAC6PDK1 | |
| SCHEMBL3454327 | 0.79 | CA12 (0.62) | HDAC1HDAC7HDAC8HDAC6CA12 | |
| SCHEMBL1310823 | 0.79 | HDAC1 (0.67) | HDAC1HDAC7HDAC8HDAC6CA12 | |
| SCHEMBL20870704 | 0.79 | EPHX2 (0.70) | CA12CA1CA2CA9NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117447296-A | Preparation method of p-chloroiodobenzene-14C | 长沙贝塔医药科技有限公司 | 2024-01-26 | — | — | CN | claimed |
| CN-108516957-A | A kind of preparation method of amides compound | 湖南大学 | 2018-09-11 | — | — | CN | claimed |
| CN-117447296-A | Preparation method of p-chloroiodobenzene-14C | 长沙贝塔医药科技有限公司 | 2024-01-26 | — | — | CN | disclosed |
| CN-117447296-A | Preparation method of p-chloroiodobenzene-14C | 长沙贝塔医药科技有限公司 | 2024-01-26 | — | — | CN | disclosed |
| CN-114507867-B | Preparation method of fluoroamide derivative | 哈尔滨工业大学（深圳） | 2023-04-14 | — | — | CN | disclosed |
| CN-114507867-A | Preparation method of fluoroamide derivative | 哈尔滨工业大学（深圳） | 2022-05-17 | — | — | CN | disclosed |
| CN-108516957-A | A kind of preparation method of amides compound | 湖南大学 | 2018-09-11 | — | — | CN | disclosed |
| US-7282609-B2 | Process for production of 1-aryl-5-(trifluoromethyl)-1H-tetrazoles | TOYO KASEI KOGYO COMPANY LIMITED (JP) | 2007-10-16 | — | — | US | disclosed |
| US-20070106080-A1 | Process for production of 1-aryl-5-(trifluoromethyl)-1h-tetrazoles | TOYO KASEI KOGYO COMPANY LIMITED (JP) | 2007-05-10 | — | — | US | disclosed |
| EP-1671945-A1 | PROCESS FOR PRODUCTION OF 1-ARYL-5-(TRIFLUOROMETHYL)-1H- TETRAZOLES | Toyo Kasei Kogyo Company Limited (JP) | 2006-06-21 | — | — | EP | disclosed |
| US-6921821-B2 | Antagonists of melanin concentrating hormone receptor | ABBOTT LABORATORIES (US) | 2005-07-26 | — | — | US | disclosed |
| EP-1534703-A2 | ANTAGONISTS OF MELANIN CONCENTRATING HORMONE RECEPTOR | ABBOTT LABORATORIES (US) | 2005-06-01 | — | — | EP | disclosed |
| US-20040106645-A1 | Antagonists of melanin concentrating hormone receptor | MILLENNIUM PHARMACEUTICALS, INC. | 2004-06-03 | — | — | US | disclosed |
| WO-2003106452-A2 | ANTAGONISTS OF MELANIN CONCENTRATING HORMONE RECEPTOR | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2003-12-24 | — | — | WO | disclosed |
| EP-0365763-A1 | Antiproliferative cyclic compounds | AGOURON PHARMACEUTICALS, INC. (US) | 1990-05-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070106080-A1 | Process for production of 1-aryl-5-(trifluoromethyl)-1h-tetrazoles | TH, NAT1, PAH | HDAC1 2913/4885HDAC7 3308/4885HDAC8 3954/4885 |
| US-20040106645-A1 | Antagonists of melanin concentrating hormone receptor | MCHR1, MCHR2, MC1R | HDAC1 2175/4885HDAC7 3236/4885HDAC8 3808/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.