Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 2/20 | 0.39 |
| ▸ | AKT2 | P31751 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TEK | Q02763 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5261288 | 0.87 | ALDH1A1 (0.53) | AKT1AKT2GAAPOLBMAPT | |
| SCHEMBL5260224 | 0.85 | AKT1 (0.41) | AKT1AKT2GAATP53POLB | |
| SCHEMBL5261110 | 0.84 | AKT1 (0.38) | AKT1AKT2GAATP53POLB | |
| SCHEMBL5263097 | 0.83 | CYP1A2 (0.42) | AKT1AKT2GAATP53POLB | |
| SCHEMBL5263504 | 0.83 | AKT1 (0.42) | AKT1AKT2GAATP53POLB | |
| SCHEMBL5263328 | 0.83 | SYK (0.42) | AKT1AKT2GAATP53POLB | |
| SCHEMBL5803806 | 0.82 | AKT1 (0.41) | AKT1AKT2GAATP53POLB | |
| SCHEMBL5261912 | 0.80 | AKT1 (0.47) | AKT1AKT2GAATP53POLB | |
| SCHEMBL5267924 | 0.80 | MAPK14 (0.41) | AKT1AKT2GAATP53POLB | |
| SCHEMBL5267408 | 0.80 | AKT1 (0.38) | AKT1AKT2GAATP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660500-B1 | SUBSTITUTED IMIDAZOPYRIMIDINES FOR THE PREVENTION AND TREATMENT OF CANCER | S A L V A T LAB SA (ES) | 2007-12-12 | — | — | EP | disclosed |