Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | AKT2 | P31751 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TEK | Q02763 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5263386 | 0.87 | ALDH1A1 (0.51) | CYP1A2CYP2C9CYP2C19SMN1; SMN2L3MBTL1 | |
| SCHEMBL5260646 | 0.83 | AKT1 (0.39) | SMN1; SMN2AKT1AKT2TP53POLB | |
| SCHEMBL5262769 | 0.81 | AKT1 (0.40) | AKT1AKT2TP53POLBGAA | |
| SCHEMBL5261110 | 0.81 | AKT1 (0.38) | CYP1A2CYP2C9CYP2C19SMN1; SMN2AKT1 | |
| SCHEMBL5263328 | 0.80 | SYK (0.42) | SMN1; SMN2AKT1AKT2KMT2ATP53 | |
| SCHEMBL5803806 | 0.79 | AKT1 (0.41) | SMN1; SMN2L3MBTL1AKT1AKT2TP53 | |
| SCHEMBL5264269 | 0.79 | AKT1 (0.41) | SMN1; SMN2AKT1AKT2TP53POLB | |
| SCHEMBL5260224 | 0.79 | AKT1 (0.41) | SMN1; SMN2AKT1AKT2TP53POLB | |
| SCHEMBL5789311 | 0.77 | GAA (0.43) | SMN1; SMN2L3MBTL1AKT1AKT2TP53 | |
| SCHEMBL5262520 | 0.77 | AKT1 (0.47) | SMN1; SMN2L3MBTL1AKT1AKT2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660500-B1 | SUBSTITUTED IMIDAZOPYRIMIDINES FOR THE PREVENTION AND TREATMENT OF CANCER | S A L V A T LAB SA (ES) | 2007-12-12 | — | — | EP | disclosed |