Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | PPARA | Q07869 | 2/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5262517 | 0.94 | NLRP3 (0.33) | NLRP3PPARGPPARA | |
| SCHEMBL5262851 | 0.94 | NLRP3 (0.33) | NLRP3 | |
| SCHEMBL5264252 | 0.93 | PPARG (0.33) | PPARGPPARADRD1 | |
| SCHEMBL5263308 | 0.87 | PPARG (0.33) | PPARGPPARADRD1 | |
| SCHEMBL5313936 | 0.86 | EGLN1 (0.31) | PPARGPPARADRD1 | |
| SCHEMBL5335132 | 0.84 | ELANE (0.34) | NLRP3ELANE | |
| SCHEMBL5260662 | 0.80 | DRD1 (0.32) | DRD1 | |
| SCHEMBL5260665 | 0.80 | EGLN1 (0.31) | DRD1 | |
| SCHEMBL5260171 | 0.79 | SCN9A (0.43) | NLRP3PPARGPPARA | |
| SCHEMBL5264792 | 0.79 | SCN9A (0.38) | NLRP3PPARGPPARADRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1332132-B1 | ENAMINE DERIVATIVES AS CELL ADHESION MOLECULES | UCB PHARMA SA (BE) | 2007-10-10 | — | — | EP | disclosed |
| US-6780874-B2 | AUTOIMMUNE DISEASE; ANTIINFLAMMATORY AGENTS; ANTIPROLIFERATIVE AGENT | CELLTECH R & D LIMITED (GB) | 2004-08-24 | — | — | US | disclosed |