Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.33 |
| ▸ | PPARA | Q07869 | 3/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.30 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.30 |
| ▸ | ITGAV | P06756 | 1/20 | 0.30 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.30 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.30 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5264252 | 0.94 | PPARG (0.33) | PPARGPPARAEGLN1ITGB1ITGB3 | |
| SCHEMBL5262517 | 0.93 | NLRP3 (0.33) | PPARGPPARA | |
| SCHEMBL5313936 | 0.92 | EGLN1 (0.31) | PPARGPPARAEGLN1DRD1 | |
| SCHEMBL5260326 | 0.90 | ITGB1 (0.38) | PPARGPPARAITGB1ITGA4 | |
| SCHEMBL5262264 | 0.90 | ITGB1 (0.38) | PPARGPPARAITGB1ITGA4 | |
| SCHEMBL5260655 | 0.87 | NLRP3 (0.34) | PPARGPPARADRD1 | |
| SCHEMBL5262851 | 0.86 | NLRP3 (0.33) | — | |
| SCHEMBL5262526 | 0.84 | DRD1 (0.31) | EGLN1DRD1 | |
| SCHEMBL5262528 | 0.82 | EGLN1 (0.30) | EGLN1 | |
| SCHEMBL5258290 | 0.82 | ITGB1 (0.35) | PPARGPPARAITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1906984-A2 | MOLECULAR COMPLEX COMPRISING ARBUTINE, ASCORBIC ACID, OLEUROPEINA OR ITS DERIVATIVES THEREOF AND RELATED USES IN MEDICAL FIELD | Med Care S.r.l. (IT) | 2008-04-09 | — | — | EP | claimed |
| WO-2006137100-A2 | MOLECULAR COMPLEX COMPRISING ARBUTINE, ASCORBIC ACID, OLEUROPEINA OR ITS DERIVATIVES THEREOF AND RELATED USES IN MEDICAL FIELD | MED CARE S.R.L. (IT) | 2006-12-28 | — | — | WO | claimed |
| EP-1332132-B1 | ENAMINE DERIVATIVES AS CELL ADHESION MOLECULES | UCB PHARMA SA (BE) | 2007-10-10 | — | — | EP | disclosed |
| US-6780874-B2 | AUTOIMMUNE DISEASE; ANTIINFLAMMATORY AGENTS; ANTIPROLIFERATIVE AGENT | CELLTECH R & D LIMITED (GB) | 2004-08-24 | — | — | US | disclosed |
| US-20030229116-A1 | ENAMINE DERIVATIVES | UCB PHARMA S.A. (BE) | 2003-12-11 | — | — | US | disclosed |
| US-6610700-B2 | Inhibit binding of integrins to their ligands, use in immune or inflammatory disorders; 3-(4-((2,6-Naphthyridinyl)amino)-phenyl)-2-((2-(1-ethylpropyl)-3-oxo-1 -cyclopentenyl) amino)-propionic acid, for example | CELLTECH R & D LIMITED (GB) | 2003-08-26 | — | — | US | disclosed |
| US-20020037909-A1 | Enamine derivatives | UCB PHARMA S.A. (BE) | 2002-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020037909-A1 | Enamine derivatives | CCR1, ITGB2, CCR10 | PPARG 407/4885PPARA 623/4885EGLN1 2242/4885 |
| US-20030229116-A1 | ENAMINE DERIVATIVES | ITGB2, CCR1, CCR10 | PPARG 474/4885PPARA 698/4885EGLN1 2049/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.