Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.38 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL74889 | 0.81 | PDPK1 (0.53) | ASH1LMAPTALDH1A1SMN1; SMN2GAA | |
| SCHEMBL5780532 | 0.79 | TLR8 (0.49) | MAPTKDM4EHIF1AHSD17B10ALDH1A1 | |
| SCHEMBL20969721 | 0.79 | KDM4E (0.42) | MAPTKDM4EHIF1AHSD17B10ALDH1A1 | |
| SCHEMBL289209 | 0.79 | ASH1L (0.44) | ASH1LMAPTALDH1A1SMN1; SMN2GAA | |
| SCHEMBL289210 | 0.79 | SMN1; SMN2 (0.56) | ASH1LMAPTHSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL9676001 | 0.79 | PSMB8 (0.56) | ASH1LMAPTKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL2747888 | 0.79 | SMN1; SMN2 (0.52) | ASH1LMAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL1619718 | 0.79 | ASH1L (0.44) | ASH1LMAPTHSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL30003135 | 0.79 | SMN1; SMN2 (0.56) | ASH1LMAPTHSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL22993546 | 0.79 | ALDH1A1 (0.55) | MAPTKDM4EHSD17B10ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110183727-B | Benzothiazole nitrogen phosphorus sulfur ternary synergistic flame retardant containing double DOPO units, and preparation method and application thereof | 三峡大学 | 2021-03-23 | — | — | CN | claimed |
| CN-110183727-A | Benzothiazole nitrogen phosphorus sulphur synergistic flame retardant containing double DOPO units, preparation method and applications | 三峡大学 | 2019-08-30 | — | — | CN | claimed |
| EP-0958295-A1 | SUBSTITUTED 2-(2,4(1H,3H)-PYRIMIDINDION-3-YL) BENZTHIAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 1999-11-24 | — | — | EP | claimed |
| WO-1998033796-A1 | SUBSTITUTED 2-(2,4(1H,3H)-PYRIMIDINDION-3-YL) BENZTHIAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 1998-08-06 | — | — | WO | claimed |
| CN-110183727-B | Benzothiazole nitrogen phosphorus sulfur ternary synergistic flame retardant containing double DOPO units, and preparation method and application thereof | 三峡大学 | 2021-03-23 | — | — | CN | disclosed |
| CN-110183727-B | Benzothiazole nitrogen phosphorus sulfur ternary synergistic flame retardant containing double DOPO units, and preparation method and application thereof | 三峡大学 | 2021-03-23 | — | — | CN | disclosed |
| US-20200071316-A1 | ACTIVATORS OF THE RETINOIC ACID INDUCIBLE GENE \"RIG-I\" PATHWAY AND METHODS OF USE THEREOF | Kineta Immuno-Oncology LLC | 2020-03-05 | — | — | US | disclosed |
| WO-2020033782-A1 | ACTIVATORS OF THE RETINOIC ACID INDUCIBLE GENE \"RIG-1\" PATHWAY AND METHODS OF USE THEREOF | Kineta, Inc. (US) | 2020-02-13 | — | — | WO | disclosed |
| CN-110183727-A | Benzothiazole nitrogen phosphorus sulphur synergistic flame retardant containing double DOPO units, preparation method and applications | 三峡大学 | 2019-08-30 | — | — | CN | disclosed |
| CN-110183727-A | Benzothiazole nitrogen phosphorus sulphur synergistic flame retardant containing double DOPO units, preparation method and applications | 三峡大学 | 2019-08-30 | — | — | CN | disclosed |
| EP-1677791-A4 | NITROGEN-CONTAINING FUSED HETEROCYCLIC COMPOUNDS | TAKEDA PHARMACEUTICAL (JP) | 2007-08-15 | — | — | EP | disclosed |
| EP-1677791-A2 | NITROGEN-CONTAINING FUSED HETEROCYCLIC COMPOUNDS | Takeda Pharmaceutical Company Limited (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005044793-A2 | NITROGEN-CONTAINING FUSED HETEROCYCLIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-05-19 | — | — | WO | disclosed |
| EP-0958295-A1 | SUBSTITUTED 2-(2,4(1H,3H)-PYRIMIDINDION-3-YL) BENZTHIAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 1999-11-24 | — | — | EP | disclosed |
| WO-1998033796-A1 | SUBSTITUTED 2-(2,4(1H,3H)-PYRIMIDINDION-3-YL) BENZTHIAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 1998-08-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200071316-A1 | ACTIVATORS OF THE RETINOIC ACID INDUCIBLE GENE \"RIG-I\" PATHWAY AND METHODS OF USE THEREOF | RARB, RARG, RARA | ASH1L 4377/4885MAPT 4826/4885KDM4E 4380/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.