Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CPA1 | P15085 | 2/20 | 0.37 |
| ▸ | CPB1 | P15086 | 1/20 | 0.37 |
| ▸ | CPA3 | P15088 | 1/20 | 0.37 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL525876 | 0.77 | TP53 (0.38) | MAPTMEN1KMT2ATSHRLMNA | |
| SCHEMBL526096 | 0.77 | CYP1A2 (0.43) | MAPTALDH1A1MEN1KMT2AGAA | |
| SCHEMBL3218987 | 0.72 | HPGD (0.48) | MAPTALDH1A1MEN1KMT2AGAA | |
| SCHEMBL12194132 | 0.69 | HPGD (0.64) | ALDH1A1MEN1KMT2AGAAHPGD | |
| SCHEMBL8778013 | 0.68 | MEN1 (0.47) | MAPTALDH1A1MEN1KMT2AGAA | |
| SCHEMBL1461837 | 0.68 | ALDH1A1 (0.56) | MAPTALDH1A1MEN1KMT2AGAA | |
| SCHEMBL526097 | 0.68 | NOTUM (0.49) | MAPTALDH1A1MEN1KMT2AGAA | |
| SCHEMBL12194134 | 0.67 | ALDH1A1 (0.51) | MAPTALDH1A1MEN1KMT2AGAA | |
| SCHEMBL10625512 | 0.67 | ALDH1A1 (0.58) | MAPTALDH1A1MEN1KMT2AGAA | |
| SCHEMBL8126677 | 0.66 | POLB (0.58) | MAPTALDH1A1MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014186-A1 | PROCESS FOR THE PREPARATION OF SILODOSIN AND ITS NOVEL INTERMEDIATES | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |