Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ENPEP | Q07075 | 4/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 4/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.31 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.30 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5262548 | 0.84 | APP (0.32) | APPALDH1A1TP53 | |
| SCHEMBL917778 | 0.84 | APP (0.34) | APPEPHX2CA2GRIA1 | |
| SCHEMBL917858 | 0.83 | APP (0.37) | APPEPHX2ALDH1A1TSHRPAOX | |
| SCHEMBL6589960 | 0.81 | APP (0.41) | APPEPHX2ALDH1A1TSHRTP53 | |
| SCHEMBL2680846 | 0.81 | APP (0.41) | APPEPHX2ALDH1A1TSHRTP53 | |
| SCHEMBL8813035 | 0.79 | TP53 (0.41) | APPEPHX2ALDH1A1TSHRTP53 | |
| SCHEMBL918312 | 0.78 | APP (0.50) | APPEPHX2ALDH1A1TSHRPAOX | |
| SCHEMBL1831247 | 0.78 | GRIA1 (0.36) | APPEPHX2ALDH1A1TP53RELA | |
| SCHEMBL918218 | 0.78 | APP (0.35) | APPEPHX2ALDH1A1TSHRGRIA1 | |
| SCHEMBL1832543 | 0.78 | GRIA1 (0.36) | APPEPHX2ALDH1A1TP53RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117338785-A | Application of GSK-126 in preparation of hypolipidemic drugs | 徐州医科大学 | 2024-01-05 | — | — | CN | disclosed |
| EP-1836161-A2 | METHODS AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES | Neurochem (International) Limited (CH) | 2007-09-26 | — | — | EP | disclosed |
| WO-2006085149-A2 | METHODS AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES | NEUROCHEM (INTERNATIONAL) LIMITED (CH) | 2006-08-17 | — | — | WO | disclosed |