Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | ENPEP | Q07075 | 4/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2680846 | 1.00 | APP (0.41) | APPTP53PTGS1PDE4ALMNA | |
| SCHEMBL8813035 | 0.93 | TP53 (0.41) | APPTP53PTGS1PDE4ALMNA | |
| SCHEMBL8810688 | 0.91 | TP53 (0.39) | APPTP53PTGS1PDE4ALMNA | |
| SCHEMBL2680752 | 0.86 | ENPEP (0.37) | APPTP53PTGS1PDE4ALMNA | |
| SCHEMBL4583294 | 0.86 | ENPEP (0.37) | APPTP53PTGS1PDE4ALMNA | |
| SCHEMBL8810924 | 0.84 | TP53 (0.45) | APPTP53BLMS1PR2S1PR1 | |
| SCHEMBL8813668 | 0.84 | TSHR (0.41) | APPTP53PTGS1PDE4ALMNA | |
| SCHEMBL16308960 | 0.84 | APP (0.42) | APPTP53PTGS1PDE4ALMNA | |
| SCHEMBL28530390 | 0.84 | APP (0.42) | APPTP53PTGS1PDE4ALMNA | |
| SCHEMBL27882009 | 0.84 | ENPEP (0.36) | APPTP53PTGS1PDE4ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0823423-B1 | 1,4-DISUBSTITUTED PIPERIDINE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2004-06-16 | — | — | EP | disclosed |
| US-5750540-A | SIDE EFFECT REDUCTION | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-05-12 | — | — | US | disclosed |
| EP-0823423-A1 | 1,4-DISUBSTITUTED PIPERIDINE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-02-11 | — | — | EP | disclosed |