Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GCGR | P47871 | 1/20 | 0.36 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | KMO | O15229 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 5/20 | 0.31 |
| ▸ | MAOB | P27338 | 5/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL526244 | 0.80 | SREBF2 (0.42) | NPC1RAB9AMAPTSREBF2ALDH1A1 | |
| SCHEMBL18775204 | 0.80 | HSD11B1 (0.31) | NPC1RAB9AMAPTSREBF2ALDH1A1 | |
| SCHEMBL526393 | 0.77 | GCGR (0.37) | NPC1RAB9AMAPTGCGRSREBF2 | |
| SCHEMBL18674424 | 0.77 | MAPK14 (0.38) | MAPTALOX5MEN1KMT2AMAPK14 | |
| SCHEMBL17053270 | 0.77 | MAPK14 (0.38) | MAPTALOX5MEN1KMT2AMAPK14 | |
| SCHEMBL526236 | 0.76 | GCGR (0.33) | NPC1RAB9AMAPTGCGRPTGES | |
| SCHEMBL526884 | 0.76 | GCGR (0.36) | NPC1RAB9AMAPTGCGRSREBF2 | |
| SCHEMBL17053349 | 0.76 | MAPK14 (0.38) | MAPTSREBF2ALOX5MEN1KMT2A | |
| SCHEMBL526739 | 0.76 | PLA2G4A (0.34) | NPC1RAB9AMAPTSREBF2ALOX5 | |
| SCHEMBL4078749 | 0.75 | GCGR (0.44) | GCGRKMORARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012013719-A1 | NEW CYCLOMETALATED COMPLEXES FOR SOLAR CELLS | UNIVERSITA' DEGLI STUDI DI MILANO BICOCCA (IT) | 2012-02-02 | — | — | WO | disclosed |