⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10777740 | 0.82 | HCAR2 (0.41) | — | |
| SCHEMBL9719706 | 0.79 | — | — | |
| SCHEMBL1852714 | 0.79 | ATM (0.50) | — | |
| SCHEMBL11099621 | 0.78 | ALDH1A1 (0.43) | — | |
| SCHEMBL11244440 | 0.77 | NAAA (0.47) | — | |
| SCHEMBL10874734 | 0.76 | TSHR (0.39) | — | |
| SCHEMBL11298415 | 0.74 | — | — | |
| SCHEMBL27590064 | 0.74 | — | — | |
| SCHEMBL25803980 | 0.74 | — | — | |
| SCHEMBL20870669 | 0.74 | ALDH1A1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1751152-A2 | AZINYL IMIDAZOAZINE AND AZINYL CARBOXAMIDE | Bayer CropScience Aktiengesellschaft (DE) | 2007-02-14 | — | — | EP | claimed |
| US-7173135-B2 | Substituted 3-cyanoquinolines as MEK inhibitors | ASTRAZENECA AB (SE) | 2007-02-06 | — | — | US | claimed |
| WO-2005113553-A2 | AZINYL IMIDAZOAZINE AND AZINYL CARBOXAMIDE | BAYER CROPSCIENCE AG (DE) | 2005-12-01 | — | — | WO | claimed |
| EP-1751152-A2 | AZINYL IMIDAZOAZINE AND AZINYL CARBOXAMIDE | Bayer CropScience Aktiengesellschaft (DE) | 2007-02-14 | — | — | EP | disclosed |
| WO-2005113553-A2 | AZINYL IMIDAZOAZINE AND AZINYL CARBOXAMIDE | BAYER CROPSCIENCE AG (DE) | 2005-12-01 | — | — | WO | disclosed |
| US-5939398-A | ANTIATHEROSCLEROSIS AGENTS | PFIZER INC. (US) | 1999-08-17 | — | — | US | disclosed |
| EP-0596406-A1 | Imidazo (1,2-a) Pyridines as bradykinin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-05-11 | — | — | EP | disclosed |
| EP-0025842-B1 | PEPTIDES, PROCESS FOR THEIR PREPARATION, THEIR PHARMACEUTICAL COMPOSITIONS AND THEIR INTERMEDIATES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-06-03 | — | — | EP | disclosed |
| EP-0021678-B1 | 1-SULPHO-2-OXOAZETIDINE DERIVATIVES, THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS THEREOF | Takeda Chemical Industries, Ltd. (JP) | 1984-11-07 | — | — | EP | disclosed |
| EP-0053387-A1 | Method of preparing 1-sulfo-2-oxoazetidine derivatives and intermediates therefor | Takeda Chemical Industries, Ltd. (JP) | 1982-06-09 | — | — | EP | disclosed |