Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 3/20 | 0.39 |
| ▸ | IDH1 | O75874 | 4/20 | 0.36 |
| ▸ | IDH2 | P48735 | 3/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 11/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19583716 | 0.76 | MALT1 (0.42) | MALT1IDH1IDH2GRM2 | |
| SCHEMBL13162796 | 0.76 | LOXL2 (0.43) | MALT1IDH1IDH2GRM2 | |
| SCHEMBL3662853 | 0.76 | MALT1 (0.42) | MALT1IDH1IDH2GRM2 | |
| SCHEMBL8224424 | 0.76 | MALT1 (0.42) | MALT1IDH1IDH2GRM2 | |
| SCHEMBL8171795 | 0.76 | IDH1 (0.42) | MALT1IDH1IDH2GRM2 | |
| Hydrochloric Acid SCHEMBL30798663 | 0.74 | LOXL2 (0.44) | MALT1IDH1IDH2GRM2 | |
| Hydrochloric Acid SCHEMBL20815622 | 0.74 | MALT1 (0.41) | MALT1IDH1IDH2GRM2 | |
| Hydrochloric Acid SCHEMBL30813051 | 0.74 | MALT1 (0.41) | MALT1IDH1IDH2GRM2 | |
| SCHEMBL17665630 | 0.74 | MALT1 (0.38) | MALT1GRM2 | |
| SCHEMBL8225228 | 0.73 | IDH1 (0.40) | MALT1IDH1IDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2906544-A1 | SUBSTITUTED PHENYLCARBAMATE COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2015-08-19 | — | — | EP | disclosed |
| WO-2014056958-A1 | SUBSTITUTED PHENYLCARBAMATE COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2014-04-17 | — | — | WO | disclosed |
| EP-1786803-A1 | PYRIMIDINYLPYRAZOLES AS TGF-BETA INHIBITORS | Biogen Idec MA, Inc. (US) | 2007-05-23 | — | — | EP | disclosed |
| WO-2006026305-A1 | PYRIMIDINYLPYRAZOLES AS TGF-BETA INHIBITORS | BIOGEN IDEC MA INC (US) | 2006-03-09 | — | — | WO | disclosed |