Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL2219621 | 0.93 | — | — | |
| Bicarbonate SCHEMBL29004812 | 0.87 | — | — | |
| Acetic Acid SCHEMBL5837058 | 0.82 | FFAR3 (0.70) | — | |
| Acetic Acid SCHEMBL8736141 | 0.82 | FFAR3 (0.70) | — | |
| Acetic Acid SCHEMBL9051977 | 0.82 | — | — | |
| Acetic Acid SCHEMBL4773693 | 0.82 | FFAR3 (0.47) | — | |
| Acetic Acid SCHEMBL3359645 | 0.78 | FFAR3 (0.64) | — | |
| Acetic Acid SCHEMBL6290880 | 0.78 | FFAR3 (0.64) | — | |
| Acetic Acid SCHEMBL15689783 | 0.78 | FFAR3 (0.64) | — | |
| Acetic Acid SCHEMBL6517807 | 0.78 | FFAR3 (0.64) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1594849-A4 | COMPOUNDS, COMPOSITIONS, AND METHODS | CYTOKINETICS INC (US) | 2007-07-04 | — | — | EP | disclosed |
| US-20070149500-A1 | Compounds, compositions, and methods | CYTOKINETICS, INCORPORATED | 2007-06-28 | — | — | US | disclosed |
| EP-1594849-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2005-11-16 | — | — | EP | disclosed |
| WO-2004064741-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | CYTOKINETICS INC. (US) | 2004-08-05 | — | — | WO | disclosed |