Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 5/20 | 0.46 |
| ▸ | NR3C2 | P08235 | 5/20 | 0.46 |
| ▸ | PGR | P06401 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | FGB | P02675 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | S100A4 | P26447 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KRAS | P01116 | 4/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4068402 | 0.78 | NR3C1 (0.76) | NR3C1NR3C2PGRMAPTGAA | |
| SCHEMBL4439342 | 0.73 | NR3C1 (0.39) | NR3C1NR3C2PGRMAPTGAA | |
| SCHEMBL4437812 | 0.72 | NR3C1 (0.45) | NR3C1NR3C2PGRMAPTGAA | |
| SCHEMBL4438824 | 0.72 | NR3C1 (0.45) | NR3C1NR3C2PGRMAPTMEN1 | |
| SCHEMBL4446861 | 0.70 | NR3C1 (0.45) | NR3C1NR3C2PGRMAPTMEN1 | |
| SCHEMBL4438777 | 0.70 | NR3C1 (0.45) | NR3C1NR3C2PGRMAPTMEN1 | |
| SCHEMBL4068656 | 0.69 | NR3C1 (0.76) | NR3C1NR3C2PGRMAPTGAA | |
| SCHEMBL5262079 | 0.69 | NR3C1 (0.39) | NR3C1NR3C2PGRMAPTAR | |
| SCHEMBL2382637 | 0.68 | HTR2A (0.54) | ARHTR2AHTR2CNTSR1KRAS | |
| SCHEMBL4067675 | 0.68 | NR3C1 (0.80) | NR3C1NR3C2PGRMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1836166-A2 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2007-09-26 | — | — | EP | disclosed |
| WO-2006071609-A2 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2006-07-06 | — | — | WO | disclosed |