Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 14/20 | 0.47 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5440972 | 0.92 | PTPN11 (0.45) | PTPN11SLC18A3SIGMAR1KCNH2 | |
| SCHEMBL5433751 | 0.83 | KMT2A (0.42) | PTPN11SLC18A3SIGMAR1KCNH2 | |
| SCHEMBL5266439 | 0.82 | PTPN11 (0.42) | PTPN11SLC18A3SIGMAR1KCNH2 | |
| SCHEMBL5432605 | 0.79 | KCNH2 (0.49) | KCNH2 | |
| SCHEMBL5266043 | 0.79 | KCNH2 (0.62) | KCNH2 | |
| SCHEMBL5266886 | 0.77 | KCNH2 (0.48) | PTPN11KCNH2 | |
| SCHEMBL5432729 | 0.77 | KCNH2 (0.39) | SLC18A3SIGMAR1KCNH2 | |
| SCHEMBL5432490 | 0.77 | PTPN11 (0.35) | PTPN11KCNH2 | |
| SCHEMBL5744809 | 0.77 | KCNH2 (0.50) | PTPN11KCNH2 | |
| SCHEMBL5744804 | 0.77 | KCNH2 (0.50) | PTPN11KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070244103-A1 | Novel Compounds Having an Anti-Bacterial Activity | MORPHOCHEM AKTIENGESELLSCHAFT FUR KOMBINATORISCHE CHEMIE (DE) | 2007-10-18 | — | — | US | disclosed |
| EP-1781650-A1 | NOVEL COMPOUNDS HAVING AN ANTI-BACTERIAL ACTIVITY | Morphochem Aktiengesellschaft Für Kombinatorische Chemie (DE) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006021448-A1 | NOVEL COMPOUNDS HAVING AN ANTI-BACTERIAL ACTIVITY | Morphochem Aktiengesellschaft für kombinatorische Chemie (DE) | 2006-03-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070244103-A1 | Novel Compounds Having an Anti-Bacterial Activity | TOP1, TOP2A, TOP2B | PTPN11 4460/4885SLC18A3 4605/4885SIGMAR1 1453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.