Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11345617 | 0.87 | MAPT (0.32) | TDP1 | |
| SCHEMBL1250604 | 0.87 | CA12 (0.34) | TDP1ALDH1A1TSHR | |
| SCHEMBL2221793 | 0.81 | — | — | |
| SCHEMBL6238242 | 0.77 | TDP1 (0.35) | TDP1TSHR | |
| Hydrochloric Acid SCHEMBL7805288 | 0.77 | ACHE (0.41) | TSHR | |
| SCHEMBL327516 | 0.75 | ALDH1A1 (0.35) | TDP1ALDH1A1 | |
| SCHEMBL6682180 | 0.75 | TSHR (0.39) | TDP1ALDH1A1TSHR | |
| SCHEMBL11347329 | 0.73 | — | — | |
| SCHEMBL526286 | 0.73 | TDP1 (0.42) | TDP1ALDH1A1 | |
| SCHEMBL9814628 | 0.72 | TDP1 (0.36) | TDP1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3200840-B1 | LOW-WATER CONTENT ACRYLATE-ACRYLAMIDE COPOLYMERS FOR OPHTHALMIC DEVICES | ALCON INC (CH) | 2021-11-17 | — | — | EP | claimed |
| EP-3200839-B1 | HYDROPHOBIC ACRYLATE-ACRYLAMIDE COPOLYMERS FOR OPHTHALMIC DEVICES | NOVARTIS AG (CH) | 2019-09-04 | — | — | EP | claimed |
| EP-3223870-B1 | WET-PACK INTRAOCULAR LENS MATERIALS WITH HIGH REFRACTIVE INDEX | NOVARTIS AG (CH) | 2018-09-26 | — | — | EP | claimed |
| US-10064977-B2 | Wet-pack intraocular lens materials with high refractive index | NOVARTIS AG (CH) | 2018-09-04 | — | — | US | claimed |
| US-9921341-B2 | Low-water content acrylate-acrylamide copolymers for ophthalmic devices | NOVARTIS AG (CH) | 2018-03-20 | — | — | US | claimed |
| US-9864102-B2 | Hydrophobic acrylate-acrylamide copolymers for ophthalmic devices | NOVARTIS AG (CH) | 2018-01-09 | — | — | US | claimed |
| EP-3223870-A1 | WET-PACK INTRAOCULAR LENS MATERIALS WITH HIGH REFRACTIVE INDEX | Novartis AG (CH) | 2017-10-04 | — | — | EP | claimed |
| WO-2016133656-A1 | WET-PACK INTRAOCULAR LENS MATERIALS WITH HIGH REFRACTIVE INDEX | NOVARTIS AG (CH) | 2016-08-25 | — | — | WO | claimed |
| US-20160235886-A1 | WET-PACK INTRAOCULAR LENS MATERIALS WITH HIGH REFRACTIVE INDEX | ALCON INC. (CH) | 2016-08-18 | — | — | US | claimed |
| US-20160170092-A1 | HYDROPHOBIC ACRYLATE-ACRYLAMIDE COPOLYMERS FOR OPHTHALMIC DEVICES | ALCON INC. (CH) | 2016-06-16 | — | — | US | claimed |
| US-20160170093-A1 | LOW-WATER CONTENT ACRYLATE-ACRYLAMIDE COPOLYMERS FOR OPHTHALMIC DEVICES | ALCON INC. (CH) | 2016-06-16 | — | — | US | claimed |
| EP-3200840-B1 | LOW-WATER CONTENT ACRYLATE-ACRYLAMIDE COPOLYMERS FOR OPHTHALMIC DEVICES | ALCON INC (CH) | 2021-11-17 | — | — | EP | disclosed |
| EP-3200839-B1 | HYDROPHOBIC ACRYLATE-ACRYLAMIDE COPOLYMERS FOR OPHTHALMIC DEVICES | NOVARTIS AG (CH) | 2019-09-04 | — | — | EP | disclosed |
| EP-3223870-B1 | WET-PACK INTRAOCULAR LENS MATERIALS WITH HIGH REFRACTIVE INDEX | NOVARTIS AG (CH) | 2018-09-26 | — | — | EP | disclosed |
| US-10064977-B2 | Wet-pack intraocular lens materials with high refractive index | NOVARTIS AG (CH) | 2018-09-04 | — | — | US | disclosed |
| US-8133512-B2 | Drug delivery systems based on catonic siloxanyl macromonomers | BAUSCH & LOMB INCORPORATED (US) | 2012-03-13 | — | — | US | disclosed |
| US-20090274745-A1 | Drug delivery systems based on catonic siloxanyl macromonomers | BAUSCH & LOMB INCORPORATED (US) | 2009-11-05 | — | — | US | disclosed |
| US-20090274744-A1 | Drug delivery system based on cationic siloxanyl macromonomers | BAUSCH & LOMB INCORPORATED (US) | 2009-11-05 | — | — | US | disclosed |
| US-7579021-B2 | Drug delivery systems based on degradable cationic siloxanyl macromonomers | BAUSCH & LOMB INCORPORATED (US) | 2009-08-25 | — | — | US | disclosed |
| US-20080075780-A1 | Drug delivery systems based on degradible cationic siloxanyl macromonomers | SANTARUS, INC. | 2008-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090274744-A1 | Drug delivery system based on cationic siloxanyl macromonomers | MSR1, LPXN, SRRM2 | TDP1 3506/4885ALDH1A1 3479/4885TSHR 2302/4885 |
| US-20090274745-A1 | Drug delivery systems based on catonic siloxanyl macromonomers | MMP13, LPXN, SLC13A2 | TDP1 3872/4885ALDH1A1 1770/4885TSHR 2498/4885 |
| US-20080075780-A1 | Drug delivery systems based on degradible cationic siloxanyl macromonomers | MSR1, LPXN, SRRM2 | TDP1 3411/4885ALDH1A1 3230/4885TSHR 1721/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.