Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 7/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | PI4KA | P42356 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL249158 | 0.83 | NNMT (0.49) | MAPTACACBKDM4E | |
| SCHEMBL16935051 | 0.81 | ACACB (0.43) | MAPTACACBPIK3CDPIK3CAPIK3CB | |
| SCHEMBL12141547 | 0.80 | MAPT (0.52) | MAPTCYP19A1ACACBPIK3CDPIK3CA | |
| SCHEMBL4012600 | 0.79 | MAPT (0.49) | MAPTCYP19A1ACACBKDM4EADORA2A | |
| SCHEMBL3719442 | 0.78 | ACACB (0.40) | MAPTCYP19A1ACACBKDM4E | |
| SCHEMBL16935044 | 0.77 | PTGES (0.35) | MAPTACACBKDM4E | |
| SCHEMBL508250 | 0.77 | MAPT (0.49) | MAPTCYP19A1ACACBPIK3CDPIK3CA | |
| SCHEMBL933951 | 0.77 | KDM4E (0.57) | MAPTCYP19A1ACACBKDM4E | |
| SCHEMBL20784571 | 0.77 | MAPT (0.49) | MAPTCYP19A1ACACBPIK3CDPIK3CA | |
| SCHEMBL21909732 | 0.77 | MAPT (0.49) | MAPTCYP19A1ACACBPIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1802632-A1 | THIENO-PYRIMIDINE COMPOUNDS HAVING FUNGICIDAL ACTIVITY | Dow AgroSciences LLC (US) | 2007-07-04 | — | — | EP | disclosed |
| WO-2006047397-A1 | THIENO-PYRIMIDINE COMPOUNDS HAVING FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2006-05-04 | — | — | WO | disclosed |