Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 20/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4930401 | 0.90 | MMP13 (0.79) | MMP13 | |
| SCHEMBL4934626 | 0.89 | MMP13 (0.71) | MMP13 | |
| SCHEMBL4934683 | 0.83 | MMP13 (0.87) | MMP13 | |
| SCHEMBL4933502 | 0.80 | MMP13 (0.79) | MMP13 | |
| SCHEMBL4930771 | 0.80 | MMP13 (0.79) | MMP13 | |
| SCHEMBL3641284 | 0.80 | MMP13 (0.86) | MMP13 | |
| SCHEMBL5264073 | 0.80 | MMP13 (0.66) | MMP13 | |
| SCHEMBL4930565 | 0.80 | MMP13 (0.78) | MMP13 | |
| SCHEMBL4933798 | 0.80 | MMP13 (0.78) | MMP13 | |
| SCHEMBL4936934 | 0.80 | MMP13 (0.78) | MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1740551-A1 | HETEROCYCLIC AMIDE COMPOUND AND USE THEREOF AS AN MMP-13 INHIBITOR | Takeda Pharmaceutical Company Limited (JP) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005105760-A1 | HETEROCYCLIC AMIDE COMPOUND AND USE THEREOF AS AN MMP-13 INHIBITOR | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-11-10 | — | — | WO | disclosed |