Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.57 |
| ▸ | PYGL | P06737 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | PCNA | P12004 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12009644 | 0.87 | PCNA (0.62) | TRPV1HPGDPOLBHDAC2HDAC8 | |
| SCHEMBL7197012 | 0.86 | HPGD (0.73) | TRPV1PYGLHPGDPOLBKDM4E | |
| SCHEMBL7888252 | 0.86 | HPGD (0.73) | TRPV1PYGLHPGDPOLBKDM4E | |
| SCHEMBL7892872 | 0.86 | LMNA (0.60) | TRPV1PYGLHPGDPOLBHDAC2 | |
| SCHEMBL8387272 | 0.86 | HPGD (0.73) | TRPV1PYGLHPGDPOLBKDM4E | |
| SCHEMBL7201453 | 0.86 | HPGD (0.73) | TRPV1PYGLHPGDPOLBKDM4E | |
| SCHEMBL17589255 | 0.86 | HPGD (0.72) | TRPV1PYGLHPGDHDAC2HDAC8 | |
| SCHEMBL19365038 | 0.84 | HPGD (0.54) | TRPV1PYGLHPGDPOLBHDAC2 | |
| SCHEMBL7778138 | 0.84 | HPGD (0.74) | TRPV1HPGDHDAC2HDAC8HDAC1 | |
| SCHEMBL2379821 | 0.83 | KDM4E (0.65) | HPGDPOLBHDAC2HDAC8GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1080065-B1 | A METHOD OF PERMANENT FLUORESCENT ASSAY | PERKINELMER LAS INC (US) | 2007-10-03 | — | — | EP | disclosed |
| EP-1129214-B1 | ENHANCED CATALYZED REPORTER DEPOSITION | NEN LIFE SCIENCE PROD INC (US) | 2005-02-02 | — | — | EP | disclosed |
| US-6593100-B2 | Enhancing the reaction of a conjugate comprising a detectably labeled phenol substrate with a peroxidase by reacting in the presence of an inorganic compound e.g. NACl, and an organic compound, e.g. p-iodophenol; signal amplification immunoassay | NEN LIFE SCIENCE PRODUCTS, INC. | 2003-07-15 | — | — | US | disclosed |
| EP-1080065-A4 | A METHOD OF PERMANENT FLUORESCENT ASSAY | NEN LIFE SCIENCE PROD INC (US) | 2003-02-12 | — | — | EP | disclosed |
| US-6518036-B1 | A method for performing a peroxidase-based assay by reacting a peroxidase enzyme with a soluble organic p-hydroxyphenyl-compound which becomes highly fluorescent after illumination, upon excitation. | NEN LIFE SCIENCE PRODUCTS, INC. | 2003-02-11 | — | — | US | disclosed |
| EP-1129214-A4 | ENHANCED CATALYZED REPORTER DEPOSITION | NEN LIFE SCIENCE PROD INC (US) | 2002-06-19 | — | — | EP | disclosed |
| US-6372937-B1 | COMPOUND WHICH ENHANCES REACTIVITY OF PEROXIDASE FOR USE IN CATALYZED REPORTER DEPOSITION | WASHINGTON UNIVERSITY | 2002-04-16 | — | — | US | disclosed |
| US-20010039035-A1 | Enhanced catalyzed reporter deposition | MEN LIFE SCIENCE PRODUCTS, INC. | 2001-11-08 | — | — | US | disclosed |
| EP-1129214-A1 | ENHANCED CATALYZED REPORTER DEPOSITION | NEN Life Science Products, Inc. (US) | 2001-09-05 | — | — | EP | disclosed |
| EP-1080065-A1 | A METHOD OF PERMANENT FLUORESCENT ASSAY | NEN Life Science Products, Inc. (US) | 2001-03-07 | — | — | EP | disclosed |
| WO-2000055115-A1 | A METHOD OF PERMANENT FLUORESCENT ASSAY | NEN LIFE SCIENCE PRODUCTS, INC. (US) | 2000-09-21 | — | — | WO | disclosed |
| WO-2000028077-A1 | ENHANCED CATALYZED REPORTER DEPOSITION | NEN LIFE SCIENCE PRODUCTS, INC. (US) | 2000-05-18 | — | — | WO | disclosed |