Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18543226 | 0.76 | ALDH1A1 (0.44) | ALDH1A1GAATP53MAPTLMNA | |
| SCHEMBL5263610 | 0.72 | ALDH1A1 (0.47) | ALDH1A1GAATP53MAPTLMNA | |
| SCHEMBL2983992 | 0.71 | ALDH1A1 (0.68) | ALDH1A1GAATP53MAPTLMNA | |
| SCHEMBL2991408 | 0.70 | ALDH1A1 (0.62) | ALDH1A1GAATP53MAPTLMNA | |
| SCHEMBL4441268 | 0.70 | SLC6A2 (0.43) | LMNAKMT2A | |
| SCHEMBL29101213 | 0.69 | OPRM1 (0.49) | ALDH1A1GAATP53MAPTLMNA | |
| SCHEMBL16292046 | 0.69 | SLC6A2 (0.70) | ALDH1A1GAATP53MAPTLMNA | |
| SCHEMBL24908661 | 0.67 | ALDH1A1 (0.45) | ALDH1A1GAATP53MAPTLMNA | |
| SCHEMBL2997199 | 0.67 | ALDH1A1 (0.69) | ALDH1A1GAATP53MAPTLMNA | |
| SCHEMBL8112308 | 0.67 | SLC6A2 (0.44) | LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1790641-A1 | TRIAZOLE DERIVATIVE OR SALT THEREOF | Astellas Pharma Inc. (JP) | 2007-05-30 | — | — | EP | disclosed |