Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.50 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.46 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.46 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.46 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.46 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.46 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | RGS12 | O14924 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4943785 | 0.90 | CA2 (0.51) | CA2CAMK2APSEN1PSEN2APH1B | |
| SCHEMBL4935609 | 0.79 | DGAT1 (0.57) | CA2CAMK2APSEN1PSEN2APH1B | |
| SCHEMBL4943034 | 0.78 | CA2 (0.55) | CA2CAMK2APSEN1PSEN2APH1B | |
| SCHEMBL4936169 | 0.77 | CA2 (0.50) | CA2CAMK2APSEN1PSEN2APH1B | |
| SCHEMBL4942093 | 0.77 | CA2 (0.53) | CA2CAMK2APSEN1PSEN2APH1B | |
| SCHEMBL4943055 | 0.76 | CA2 (0.56) | CA2CAMK2APSEN1PSEN2APH1B | |
| SCHEMBL4937928 | 0.76 | CA2 (0.60) | CA2CAMK2APSEN1PSEN2APH1B | |
| SCHEMBL1679378 | 0.75 | CYP2C19 (0.66) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| Methane SCHEMBL11691361 | 0.75 | CA2 (0.55) | CA2CAMK2APSEN1PSEN2APH1B | |
| SCHEMBL4935679 | 0.74 | CA2 (0.50) | CA2CAMK2APSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1806332-A1 | BENZENE COMPOUND HAVING 2 OR MORE SUBSTITUENTS | Daiichi Sankyo Company, Limited (JP) | 2007-07-11 | — | — | EP | disclosed |