Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | ELANE | P08246 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | MARK4 | Q96L34 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13517020 | 0.94 | ATM (0.53) | ATML3MBTL1ELANETDP1SLC1A3 | |
| SCHEMBL526418 | 0.94 | ATM (0.53) | ATML3MBTL1ELANETDP1SLC1A3 | |
| Guanidine SCHEMBL10882668 | 0.91 | ATM (0.42) | ATML3MBTL1ELANETDP1SLC1A3 | |
| SCHEMBL27686554 | 0.84 | ELANE (0.40) | ELANETDP1TSHRMAPTKDM4E | |
| SCHEMBL9854114 | 0.82 | LMNA (0.52) | L3MBTL1ELANELMNAALDH1A1GAA | |
| SCHEMBL4322254 | 0.82 | LMNA (0.52) | L3MBTL1ELANELMNAALDH1A1GAA | |
| SCHEMBL3632858 | 0.82 | LMNA (0.52) | L3MBTL1ELANELMNAALDH1A1GAA | |
| SCHEMBL7869800 | 0.82 | KMT2A (0.56) | L3MBTL1TDP1HSD17B10MAPTALDH1A1 | |
| SCHEMBL27705573 | 0.82 | CYP3A4 (0.54) | ATML3MBTL1HSD17B10LMNAALDH1A1 | |
| SCHEMBL7869801 | 0.82 | KMT2A (0.56) | L3MBTL1TDP1HSD17B10MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2598160-A2 | STABILIZATION OF FSH | Ferring BV (NL) | 2013-06-05 | — | — | EP | disclosed |
| CN-101823970-B | Synthetic method of rivastigmine and intermediates thereof | JIANGSU NHWA PHARMACEUTICAL CO LTD | 2013-05-08 | — | — | CN | disclosed |
| WO-2012013742-A2 | STABILIZATION OF FSH | FERRING B.V. (NL) | 2012-02-02 | — | — | WO | disclosed |
| CN-101823970-A | Synthetic method of rivastigmine and intermediates thereof | JIANGSU NHWA PHARMACEUTICAL CO LTD | 2010-09-08 | — | — | CN | disclosed |
| US-5763490-A | ADMINISTERING AN ENZYME INHIBITOR TO INHIBIT PROSTATIC ACID PHOSPHATASE | UNIVERSITY OF SOUTH CAROLINA (US) | 1998-06-09 | — | — | US | disclosed |