SCHEMBL7869800

SCHEMBL7869800

O=C(O)C(O)C(O)C(=O)Oc1ccc2ccccc2c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.56
MEN1 O00255 2/20 0.56
MAPT P10636 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
PPARG P37231 5/20 0.49
PPARA Q07869 5/20 0.49
PTPN7 P35236 1/20 0.47
KDM4E B2RXH2 2/20 0.47
ALDH1A1 P00352 3/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
HSD17B10 Q99714 1/20 0.46
FABP7 O15540 1/20 0.46
FABP3 P05413 1/20 0.46
MMP1 P03956 2/20 0.43
MMP12 P39900 1/20 0.43
PPARD Q03181 2/20 0.43
BCHE P06276 1/20 0.42
FAAH O00519 1/20 0.42
EPHX1 P07099 1/20 0.42
MMP2 P08253 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7869801 1.00 KMT2A (0.56) KMT2AMEN1MAPTTDP1PPARG
SCHEMBL28172274 0.82 KMT2A (0.58) KMT2AMEN1MAPTTDP1PPARG
SCHEMBL526417 0.82 ATM (0.49) MAPTTDP1KDM4EALDH1A1L3MBTL1
SCHEMBL18256 0.79 KMT2A (0.54) KMT2AMEN1MAPTTDP1PPARG
SCHEMBL10325206 0.79 KMT2A (0.54) KMT2AMEN1MAPTTDP1PPARG
SCHEMBL11600998 0.79 KMT2A (0.54) KMT2AMEN1MAPTTDP1PPARG
SCHEMBL11600993 0.78 KMT2A (0.57) KMT2AMEN1MAPTTDP1PPARG
Hydrochloric Acid SCHEMBL7736403 0.78 KMT2A (0.53) KMT2AMEN1MAPTTDP1PPARG
Phosphine SCHEMBL9464028 0.78 KMT2A (0.53) KMT2AMEN1MAPTTDP1PPARG
Ammonia Solution, Strong SCHEMBL2067052 0.78 KMT2A (0.53) KMT2AMEN1MAPTTDP1PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1094808-A1 THERAPEUTIC COMBINATIONS COMPRISING A SELECTIVE ESTROGEN RECEPTOR MODULATOR AND PARATHYROID HORMONE Pfizer Products Inc. (US) 2001-05-02 EP disclosed
EP-1087764-A1 THERAPEUTIC COMBINATIONS OF (SELECTIVE) ESTROGEN RECEPTOR MODULATORS (SERM) AND GROWTH HORMONE SECRETAGOGUES (GHS) FOR TREATING MUSCULOSKELETAL FRAILTY Pfizer Products Inc. (US) 2001-04-04 EP disclosed
EP-1085867-A1 THERAPEUTIC COMBINATIONS OF (SELECTIVE) ESTROGEN RECEPTOR MODULATORS (SERM) AND GROWTH HORMONE SECRETAGOGUES (GHS) FOR TREATING MUSCULOSKELETAL FRAILTY Pfizer Products Inc. (US) 2001-03-28 EP disclosed
WO-1999065486-A1 THERAPEUTIC COMBINATIONS OF (SELECTIVE) ESTROGEN RECEPTOR MODULATORS (SERM) AND GROWTH HORMONE SECRETAGOGUES (GHS) FOR TREATING MUSCULOSKELETAL FRAILTY PFIZER PRODUCTS, INC. (US) 1999-12-23 WO disclosed
WO-1999065488-A1 THERAPEUTIC COMBINATIONS OF (SELECTIVE) ESTROGEN RECEPTOR MODULATORS (SERM) AND GROWTH HORMONE SECRETAGOGUES (GHS) FOR TREATING MUSCULOSKELETAL FRAILTY PFIZER PRODUCTS INC. (US) 1999-12-23 WO disclosed
WO-1999065482-A1 THERAPEUTIC COMBINATIONS COMPRISING A SELECTIVE ESTROGEN RECEPTOR MODULATOR AND PARATHYROID HORMONE PFIZER PRODUCTS INC. (US) 1999-12-23 WO disclosed