SCHEMBL526452

SCHEMBL526452

Nc1cccc(Br)c1O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29810697 1.00
Hydrochloric Acid SCHEMBL4969077 0.97 MMP2 (0.45)
SCHEMBL416446 0.80
SCHEMBL1172644 0.80
SCHEMBL14840044 0.77 CRHBP (0.46)
Hydrochloric Acid SCHEMBL10875382 0.77 MMP2 (0.54)
SCHEMBL724770 0.72
SCHEMBL5556 0.72
SCHEMBL69568 0.72
SCHEMBL1013212 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 562 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115322110-B Method for synthesizing eltrombopag intermediate 3 '-amino-2' -hydroxybiphenyl-3-carboxylic acid 常熟理工学院 2024-03-19 CN claimed
CN-112321454-B Eltrombopag intermediate, preparation method thereof and method for preparing Ai Qubo Pa by using same 长沙创新药物工业技术研究院有限公司 2023-03-17 CN claimed
CN-115322110-A Method for synthesizing eltrombopag intermediate 3 '-amino-2' -hydroxybiphenyl-3-carboxylic acid 常熟理工学院 2022-11-11 CN claimed
CN-113862702-A Synthesis method for preparing phenoxazinone compound by electrochemically oxidizing o-aminophenol analog 温州医科大学 2021-12-31 CN claimed
CN-112321454-A Elotriporpa intermediate, preparation method thereof and method for preparing Elotriporpa by using intermediate 湖南华腾制药有限公司 2021-02-05 CN claimed
CN-108191763-A A kind of synthetic method of Ai Qu pools pa ethanol amine 扬子江药业集团四川海蓉药业有限公司 2018-06-22 CN claimed
US-12637449-B2 Organic compound and organic light emitting device including the same LG DISPLAY CO., LTD. (KR) 2026-05-26 US disclosed
CN-122036680-A Anti-fibrotic pyridones 英特穆恩公司 2026-05-15 CN disclosed
WO-2026098667-A1 USP30 INHIBITOR COMPOUND, PHARMACEUTICAL COMPOSITION, PREPARATION METHOD THEREFOR, AND USE THEREOF 长春金赛药业有限责任公司 2026-05-15 WO disclosed
EP-4735452-A2 HETEROBIFUNCTIONAL COMPOUNDS FOR THE DEGRADATION OF KRAS PROTEIN Merck Patent GmbH (DE) 2026-05-06 EP disclosed
EP-4735438-A2 HETEROBIFUNCTIONAL COMPOUNDS FOR THE DEGRADATION OF KRAS Merck Patent GmbH (DE) 2026-05-06 EP disclosed
EP-3886904-B1 IRAK DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS INC (US) 2026-04-22 EP disclosed
US-20260083721-A1 7-CYANO-8-HYDROXYQUINOLINE DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF JIANGSU YAHONG MEDITECH CO LTD (CN) 2026-03-26 US disclosed
US-6372770-B1 TREATING A MAMMAL SUFFERING FROM A DISEASE STATE SELECTED FROM THE GROUP CONSISTING OF ASTHMA, ALLERGIES, INFLAMMATION, DEPRESSION, DEMENTIA, ATOPIC DISEASES, RHINITIS AND DISEASE STATES ASSOCIATED WITH ABNORMALLY HIGH PHYSIOLOGICAL LEVELS OF EURO-CELTIQUE, S.A. 2002-04-16 US disclosed
US-6365606-B1 TREATMENT OF DISEASES WITH ABNORMALLY HIGH PHYSIOLOGICAL LEVELS OF CYTOKINES; SIDE EFFECT REDUCTION; ISOINDOLES; BRONCHODILATOR; ANTI-INFLAMMATORY AGENT EURO-CELTIQUE, S.A. (LU) 2002-04-02 US disclosed
EP-1160247-A1 6,5-Fused aromatic ring systems having enhanced phosphodiesterae IV inhibitory activity Euro-Celtique S.A. (LU) 2001-12-05 EP disclosed
US-6075016-A 6,5-fused aromatic ring systems having enhanced phosphodiesterase IV inhibitory activity EURO-CELTIQUE S.A. (LU) 2000-06-13 US disclosed
EP-0785927-A4 NOVEL BENZOXAZOLES EURO CELTIQUE SA (LU) 1997-12-29 EP disclosed
EP-0785927-A1 NOVEL BENZOXAZOLES Euroceltique S.A. (LU) 1997-07-30 EP disclosed
WO-1996011917-A1 NOVEL BENZOXAZOLES EURO-CELTIQUE, S.A. (LU) 1996-04-25 WO disclosed