Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA4 | P22748 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SLC6A7 | Q99884 | 3/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | FASN | P49327 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5317493 | 1.00 | GHSR (0.50) | GHSRPOLBHPGDMAPK1CA1 | |
| Hydrochloric Acid SCHEMBL5316525 | 0.99 | GHSR (0.49) | GHSRPOLBHPGDMAPK1CA1 | |
| Hydrochloric Acid SCHEMBL5265791 | 0.99 | GHSR (0.49) | GHSRPOLBHPGDMAPK1CA1 | |
| SCHEMBL1090152 | 0.91 | SIGMAR1 (0.54) | HPGDCA1CA2CA4CA9 | |
| SCHEMBL1090149 | 0.91 | SIGMAR1 (0.54) | HPGDCA1CA2CA4CA9 | |
| SCHEMBL1763575 | 0.91 | SIGMAR1 (0.54) | HPGDCA1CA2CA4CA9 | |
| Hydrochloric Acid SCHEMBL3710664 | 0.90 | SIGMAR1 (0.53) | HPGDCA1CA2CA4CA9 | |
| Hydrochloric Acid SCHEMBL1763150 | 0.90 | SIGMAR1 (0.53) | HPGDCA1CA2CA4CA9 | |
| Hydrochloric Acid SCHEMBL1763147 | 0.90 | SIGMAR1 (0.53) | HPGDCA1CA2CA4CA9 | |
| SCHEMBL30671639 | 0.84 | GAA (0.50) | HPGDCA1CA2CA4CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1844052-A1 | THIENO[2,3-D]PYRIMIDINE COMPOUNDS AS INHIBITORS OF ADP-MEDIATED PLATELETS AGGREGATION | Pharmacia & Upjohn Company LLC (US) | 2007-10-17 | — | — | EP | disclosed |
| WO-2006079916-A1 | THIENO [2,3-D] PYRIMIDINE COMPOUNDS AS INHIBITORS OF ADP-MEDIATED PLATELETS AGGREGATION | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-08-03 | — | — | WO | disclosed |