Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5271051 | 0.93 | F10 (0.41) | F10CYP2C9 | |
| SCHEMBL5267728 | 0.88 | F10 (0.46) | F10 | |
| SCHEMBL4503899 | 0.88 | F10 (0.55) | F10CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5265552 | 0.85 | F10 (0.41) | F10 | |
| SCHEMBL5266654 | 0.83 | F10 (0.36) | F10 | |
| SCHEMBL4509603 | 0.81 | F10 (0.48) | F10CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5263799 | 0.81 | F10 (0.36) | F10CYP2C9 | |
| SCHEMBL2766694 | 0.81 | F10 (0.47) | F10CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5264574 | 0.79 | F10 (0.46) | F10CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5266084 | 0.78 | F10 (0.45) | F10CYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1836198-A1 | SUBSTITUTED PYRROLIDINONES HAVING AN ANTITHROMBOTIC EFFECT, THE PRODUCTION THEREOF AND THEIR USE AS MEDICAMENTS | Boehringer Ingelheim International GmbH (DE) | 2007-09-26 | — | — | EP | disclosed |
| WO-2006069946-A1 | SUBSTITUTED PYRROLIDINONES HAVING AN ANTITHROMBOTIC EFFECT, THE PRODUCTION THEREOF AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-07-06 | — | — | WO | disclosed |