Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 15/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5266197 | 0.90 | F10 (0.37) | F10ALDH1A1KMT2ACYP2C9HPGD | |
| SCHEMBL5271051 | 0.88 | F10 (0.41) | F10KDM4EALDH1A1KMT2ACYP2C9 | |
| SCHEMBL4509766 | 0.87 | F10 (0.45) | F10KMT2ACYP2C9 | |
| SCHEMBL5267728 | 0.83 | F10 (0.46) | F10 | |
| SCHEMBL5265157 | 0.82 | F10 (0.45) | F10CYP2C9 | |
| SCHEMBL5314273 | 0.82 | F10 (0.42) | F10CYP2C9 | |
| SCHEMBL5265451 | 0.81 | F10 (0.48) | F10CYP2C9 | |
| SCHEMBL5270690 | 0.80 | POLB (0.40) | F10KMT2A | |
| SCHEMBL4507911 | 0.80 | F10 (0.53) | F10CYP2C9 | |
| SCHEMBL5269982 | 0.79 | F10 (0.43) | F10CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1836198-A1 | SUBSTITUTED PYRROLIDINONES HAVING AN ANTITHROMBOTIC EFFECT, THE PRODUCTION THEREOF AND THEIR USE AS MEDICAMENTS | Boehringer Ingelheim International GmbH (DE) | 2007-09-26 | — | — | EP | disclosed |
| WO-2006069946-A1 | SUBSTITUTED PYRROLIDINONES HAVING AN ANTITHROMBOTIC EFFECT, THE PRODUCTION THEREOF AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-07-06 | — | — | WO | disclosed |