SCHEMBL5267728

SCHEMBL5267728

Cc1cc(N2CC(C)(NC(=O)Oc3ccc(Cl)s3)CC2=O)ccc1N1CCOCC1=O

nearest known ligand 0.46

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.46
F2 P00734 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5265451 0.88 F10 (0.48) F10
SCHEMBL4517868 0.87 F10 (0.57) F10F2
SCHEMBL5263799 0.83 F10 (0.36) F10
SCHEMBL5271051 0.81 F10 (0.41) F10
SCHEMBL5266888 0.80 F10 (0.47) F10F2
SCHEMBL5265157 0.80 F10 (0.45) F10F2
SCHEMBL4507911 0.79 F10 (0.53) F10
SCHEMBL5314273 0.78 F10 (0.42) F10
SCHEMBL4503899 0.77 F10 (0.55) F10
SCHEMBL5269982 0.76 F10 (0.43) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1836198-A1 SUBSTITUTED PYRROLIDINONES HAVING AN ANTITHROMBOTIC EFFECT, THE PRODUCTION THEREOF AND THEIR USE AS MEDICAMENTS Boehringer Ingelheim International GmbH (DE) 2007-09-26 EP disclosed
WO-2006069946-A1 SUBSTITUTED PYRROLIDINONES HAVING AN ANTITHROMBOTIC EFFECT, THE PRODUCTION THEREOF AND THEIR USE AS MEDICAMENTS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2006-07-06 WO disclosed