Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 2/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1532824 | 0.88 | FAAH (0.52) | ALDH1A1HTTFAAHPRMT5NAMPT | |
| Oxalic Acid SCHEMBL5265472 | 0.86 | FAAH (0.51) | ALDH1A1HTTFAAHPKMPRMT5 | |
| SCHEMBL1532799 | 0.78 | ALDH1A1 (0.55) | ALDH1A1HTTFAAHPKMNAMPT | |
| SCHEMBL1532688 | 0.77 | FAAH (0.47) | ALDH1A1HTTFAAHPRMT5 | |
| SCHEMBL1532829 | 0.76 | FAAH (0.54) | ALDH1A1HTTFAAHPRMT5 | |
| SCHEMBL12735977 | 0.76 | MRGPRX4 (0.50) | ALDH1A1HTTFAAHPKMPRMT5 | |
| SCHEMBL12735975 | 0.74 | FAAH (0.48) | ALDH1A1HTTFAAHPRMT5 | |
| SCHEMBL12735967 | 0.74 | FAAH (0.44) | ALDH1A1HTTFAAHPKMNAMPT | |
| SCHEMBL1533056 | 0.73 | FAAH (0.47) | ALDH1A1HTTFAAHPKMNAMPT | |
| SCHEMBL17559339 | 0.73 | PRMT5 (0.45) | ALDH1A1HTTPRMT5GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2607362-A1 | Piperidine and piperazine carboxylates as FAAH inhibitors | Astellas Pharma Inc. (JP) | 2013-06-26 | — | — | EP | disclosed |
| EP-1849773-A1 | PYRIDYL NON-AROMATIC NITROGENATED HETEROCYCLIC-1-CARBOXYLATE ESTER DERIVATIVE | Astellas Pharma Inc. (JP) | 2007-10-31 | — | — | EP | disclosed |