Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 4/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | PTGIR | P43119 | 1/20 | 0.31 |
| ▸ | MC4R | P32245 | 1/20 | 0.31 |
| ▸ | PAM | P19021 | 1/20 | 0.30 |
| ▸ | RBP4 | P02753 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5270565 | 0.82 | SLC6A2 (0.37) | — | |
| Hydrochloric Acid SCHEMBL4865376 | 0.81 | SLC6A2 (0.36) | MEN1KMT2A | |
| SCHEMBL30657529 | 0.69 | ALDH1A1 (0.54) | EGFRALDH1A1MAPTPTPN7 | |
| SCHEMBL5318595 | 0.62 | NPC1 (0.37) | EGFRALDH1A1MAPT | |
| SCHEMBL28046369 | 0.62 | ALDH1A1 (0.38) | ALDH1A1MAPT | |
| SCHEMBL15108157 | 0.61 | HTR2C (0.43) | ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL12837230 | 0.61 | CHRNB4 (0.34) | MEN1MAPTKMT2A | |
| SCHEMBL21933079 | 0.59 | MAPT (0.52) | ALOX15ALDH1A1MEN1MAPTPTPN7 | |
| SCHEMBL3958089 | 0.59 | EGFR (0.47) | EGFRALDH1A1 | |
| SCHEMBL2605809 | 0.59 | EGFR (0.47) | EGFRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537117-B1 | BENZOTRIAZABICYCLIC DERIVATIVES AND USE THEREOF AS BETA-LACTAMASE INHIBITORS AND ANTI-BACTERIAL AGENTS | AVENTIS PHARMA SA (FR) | 2007-01-17 | — | — | EP | disclosed |