Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 4/20 | 0.36 |
| ▸ | TDO2 | P48775 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4862019 | 0.86 | MEN1 (0.37) | IDO1ALDH1A1MAPTMAPK1 | |
| SCHEMBL5322672 | 0.79 | CASP1 (0.37) | MAPTGAAMAPK1SMN1; SMN2 | |
| SCHEMBL5254943 | 0.75 | NPC1 (0.38) | NPC1RAB9AS1PR5EPHX2ALDH1A1 | |
| SCHEMBL5187275 | 0.72 | GPR183 (0.39) | NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL5270565 | 0.71 | SLC6A2 (0.37) | NPC1RAB9AIDO1TDO2HTR1A | |
| Hydrochloric Acid SCHEMBL4865376 | 0.70 | SLC6A2 (0.36) | NPC1RAB9AIDO1TDO2HTR1A | |
| SCHEMBL5330841 | 0.68 | TSHR (0.40) | NPC1RAB9AHTR1ASLC6A2SLC6A4 | |
| SCHEMBL4697074 | 0.68 | NPC1 (0.34) | NPC1RAB9AS1PR5EPHX2ALDH1A1 | |
| SCHEMBL5187221 | 0.66 | NPC1 (0.37) | NPC1RAB9AEPHX2ALDH1A1MAPT | |
| SCHEMBL3305431 | 0.65 | LMNA (0.34) | NPC1RAB9AS1PR5EPHX2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537117-B1 | BENZOTRIAZABICYCLIC DERIVATIVES AND USE THEREOF AS BETA-LACTAMASE INHIBITORS AND ANTI-BACTERIAL AGENTS | AVENTIS PHARMA SA (FR) | 2007-01-17 | — | — | EP | disclosed |