⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34460214 | 1.00 | — | — | |
| SCHEMBL34460307 | 1.00 | — | — | |
| Fluoride SCHEMBL28181689 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL7545038 | 0.79 | — | — | |
| SCHEMBL6254896 | 0.69 | — | — | |
| SCHEMBL4716527 | 0.69 | — | — | |
| SCHEMBL312465 | 0.68 | — | — | |
| SCHEMBL14567930 | 0.68 | — | — | |
| SCHEMBL6623701 | 0.68 | — | — | |
| SCHEMBL997613 | 0.67 | HDAC8 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106957318-A | Fused polycycle sulfonylindoline compounds, its preparation method, pharmaceutical composition and application | 中国科学院上海有机化学研究所 | 2017-07-18 | — | — | CN | claimed |
| CN-105802128-A | Halogen-free thermosetting resin composition and prepreg and printed circuit laminated board using the same | 广东生益科技股份有限公司 | 2016-07-27 | — | — | CN | claimed |
| CN-104274831-A | Composition based on naturally derived peptide and inflammation inhibitor and/or anti-oxidation compound | SOO TUCK POOI | 2015-01-14 | — | — | CN | claimed |
| CN-101142198-A | Iso * Azacalbutastine derivatives for the treatment of disease | SYNTA PHARMACEUTICALS CORP (US) | 2008-03-12 | — | — | CN | claimed |
| CN-1088727-C | Thermosetting resin composition, solidifying material, preformed material metal armoured laminated plate and circuit board | HITACHI KASEI IND CO LTD (JP) | 2002-08-07 | — | — | CN | claimed |
| CN-117157298-A | Dual-function chimeric heterocyclic compound of interleukin-1 receptor related kinase 4, preparation method, medicinal composition and application thereof | 石药集团中奇制药技术（石家庄）有限公司 | 2023-12-01 | — | — | CN | disclosed |
| WO-2023186069-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND OF INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE 4, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | 石药集团中奇制药技术（石家庄）有限公司 | 2023-10-05 | — | — | WO | disclosed |
| WO-2023125944-A1 | COMPOUND CONTAINING HETEROCYCLIC RING | 正大天晴药业集团股份有限公司 | 2023-07-06 | — | — | WO | disclosed |
| CN-110540525-B | Synthetic method of 3-thioether-group quinoxalinone compound | 广西师范大学 | 2022-11-22 | — | — | CN | disclosed |
| CN-105884780-B | Polycyclic compound, its pharmaceutical composition and application | 上海迪诺医药科技有限公司 | 2019-11-08 | — | — | CN | disclosed |
| CN-107438611-B | fused ring compound, pharmaceutical composition and application thereof | SHANGHAI DE NOVO PHARMATECH CO.,LTD. (CN) | 2019-10-29 | — | — | CN | disclosed |
| CN-110156656-A | Five yuan of heteroaromatic ring derivatives, preparation method, pharmaceutical composition and application | 上海迪诺医药科技有限公司 | 2019-08-23 | — | — | CN | disclosed |
| CN-1878758-A | Crf antagonists and heterobicyclic compounds | ONO PHARMACEUTICAL CO (JP) | 2006-12-13 | — | — | CN | disclosed |
| WO-2006104177-A1 | ORGANOMETALLIC COMPLEX, AND LIGHT-EMITTING DEVICE AND ELECTRONIC APPLIANCE USING THE SAME | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2006-10-05 | — | — | WO | disclosed |
| CN-1150191-C | aminoalkyl substituted (benzodioxan, benzofuran or benzopyran) derivatives | ղɭҩҵ����˾ | 2004-05-19 | — | — | CN | disclosed |
| CN-1353707-A | aminoalkyl substituted (benzodioxan, benzofuran or benzopyran) derivatives | JANSSEN PHARMACEUTICA NV (BE) | 2002-06-12 | — | — | CN | disclosed |
| EP-0252670-B1 | 2-SUBSTITUTED ALKOXY-3-SUBSTITUTED-PYRAZINES | TOYO JOZO KABUSHIKI KAISHA (JP) | 1992-01-15 | — | — | EP | disclosed |
| US-5001237-A | 2-substituted alkoxy-3-substituted-pyrazines | TOYO JOZO KABUSHIKI KAISHA (JP) | 1991-03-19 | — | — | US | disclosed |
| US-4894453-A | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS | TOYO JOZO KABUSHIKI KAISHA (JP) | 1990-01-16 | — | — | US | disclosed |
| EP-0252670-A2 | 2-Substituted alkoxy-3-substituted-pyrazines | TOYO JOZO KABUSHIKI KAISHA (JP) | 1988-01-13 | — | — | EP | disclosed |