SCHEMBL5266052

SCHEMBL5266052

CCC(c1ccccc1P)P(c1ccccc1)c1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5454194 0.76 CYP3A4 (0.32)
SCHEMBL4242747 0.71 HTR2A (0.45) TSHRLMNA
SCHEMBL2231035 0.70 TSHR (0.40) TSHRLMNA
SCHEMBL18549762 0.69 TSHR (0.33) TSHRLMNA
SCHEMBL28240908 0.69 LMNA (0.37) TSHRLMNA
SCHEMBL9204533 0.69 TSHR (0.59) TSHR
Bromide SCHEMBL7932453 0.69 TSHR (0.39) TSHRLMNA
Hydrochloric Acid SCHEMBL7930534 0.69 TSHR (0.39) TSHRLMNA
SCHEMBL6569406 0.68 LMNA (0.39) TSHRLMNA
SCHEMBL115575 0.68 LMNA (0.39) TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1841534-A2 PREPARATION OF TRIDENTATE PHOSPHINES, METHOD OF FORMING ALDEHYDE HYDROGENATION CATALYSTS USING THEM AND PROCESS FOR ALDEHYDE HYDROGENATION Dow Gloval Technologies Inc. (US) 2007-10-10 EP claimed
WO-2006058184-A2 PREPARATION OF TRIDENTATE PHOSPHINES, METHOD OF FORMING ALDEHYDE HYDROGENATION CATALYSTS USING THEM AND PROCESS FOR ALDEHYDE HYDROGENATION DOW GLOBAL TECHNOLOGIES INC. (US) 2006-06-01 WO claimed