SCHEMBL115575

SCHEMBL115575

CCC(P(c1ccccc1)c1ccccc1)P(c1ccccc1)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.39
CYP3A4 P08684 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
MIF P14174 1/20 0.36
TP53 P04637 1/20 0.36
NOS3 P29474 1/20 0.34
NOS2 P35228 1/20 0.34
ESR1 P03372 2/20 0.33
ESR2 Q92731 2/20 0.33
TRPA1 O75762 2/20 0.33
KCNN4 O15554 1/20 0.33
TSHR P16473 1/20 0.32
KDM4E B2RXH2 1/20 0.32
GAA P10253 1/20 0.32
GPR84 Q9NQS5 1/20 0.31
HKDC1 Q2TB90 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4738364 0.98 LMNA (0.38) LMNACYP3A4TDP1MIFTP53
SCHEMBL14693766 0.98 LMNA (0.38) LMNACYP3A4TDP1MIFTP53
Hydrochloric Acid SCHEMBL6058391 0.98 LMNA (0.38) LMNACYP3A4TDP1MIFTP53
SCHEMBL15295495 0.98 LMNA (0.38) LMNACYP3A4TDP1MIFTP53
Hydrochloric Acid SCHEMBL1404111 0.95 LMNA (0.37) LMNACYP3A4TDP1MIFTP53
Hydrochloric Acid SCHEMBL1404110 0.95 LMNA (0.37) LMNACYP3A4TDP1MIFTP53
Bromide SCHEMBL5527408 0.95 LMNA (0.37) LMNACYP3A4TDP1MIFTP53
Hydrochloric Acid SCHEMBL1898174 0.95 LMNA (0.37) LMNACYP3A4TDP1MIFTP53
Hydrochloric Acid SCHEMBL1898172 0.95 LMNA (0.37) LMNACYP3A4TDP1MIFTP53
SCHEMBL7097256 0.93 LMNA (0.35) LMNACYP3A4TDP1MIFTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2804 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260015324-A1 Processes for Preparing 5-Bromo-3,4-dimethylpyridin-2-amine and 6-Bromo-7,8-dimethyl-[1,2,4]triazolo[1,5-a]pyridine BRISTOL MYERS SQUIBB CO (US) 2026-01-15 US claimed
WO-2025104433-A1 CATALYST AND SYNTHESIS THEREOF UNIVERSITY OF STRATHCLYDE (GB) 2025-05-22 WO claimed
CN-119546578-A Process for the preparation of 5-bromo-3, 4-dimethylpyridin-2-amine and 6-bromo-7, 8-dimethyl- [1,2,4] triazolo [1,5-a ] pyridine 百时美施贵宝公司 2025-02-28 CN claimed
CN-116354841-B Method for synthesizing formamide by catalyzing lower amine and carbon dioxide by polymer-based catalyst 中国科学院兰州化学物理研究所 2024-06-14 CN claimed
CN-118063383-A Rhodium-catalyzed coupling method of cycloheptatriene and aromatic amine 中国科学院大连化学物理研究所 2024-05-24 CN claimed
EP-4143159-B1 PREPARATION OF AROMATIC CARBOXYAMIDES BY A PALLADIUM-CATALYZED CARBONYLATION REACTION BASF SE (DE) 2024-04-10 EP claimed
EP-4337325-A1 PALLADIUM VINYL AND BUTADIENYL COMPOUNDS AS CHEMOTHERAPEUTIC AGENTS Universita' Ca' Foscari Venezia (IT) 2024-03-20 EP claimed
WO-2023178061-A1 BIOCATALYTIC SYNTHESIS OF (1S,3S)-3-HYDROXYCYCLOHEXANE-1-CARBOXYLIC ACID COMPOUNDS BRISTOL-MYERS SQUIBB COMPANY (US) 2023-09-21 WO claimed
CN-116655504-A Preparation method of diaryl sulfide compound 浙江扬帆新材料股份有限公司 2023-08-29 CN claimed
CN-116354841-A Method for synthesizing formamide by catalyzing lower amine and carbon dioxide by polymer-based catalyst 中国科学院兰州化学物理研究所 2023-06-30 CN claimed
WO-1996001690-A1 CATALYST FOR THE PREPARATION OF LINEAR CARBON MONOXIDE/ALPHA-OLEFIN COPOLYMERS THE DOW CHEMICAL COMPANY (US) 1996-01-25 WO claimed
US-5414138-A Process for producing 2-formyl-1,4-butanediol KURARAY COMPANY LTD. (JP) 1995-05-09 US claimed
EP-0627399-A1 Process for producing 2-formyl-1,4-butanediol KURARAY CO., LTD. (JP) 1994-12-07 EP claimed
EP-0587050-A1 Process for the preparation of an aromatic group substituted olefins from chloroaromatics HOECHST AKTIENGESELLSCHAFT (DE) 1994-03-16 EP claimed
EP-0283586-B1 HOMOLOGATION PROCESS UNION CARBIDE CORPORATION (US) 1993-03-17 EP claimed
EP-0283586-A2 Homologation process UNION CARBIDE CORPORATION (US) 1988-09-28 EP claimed
US-4727200-A RHODIUM-BASED CATALYST; MILD CONDITIONS UNION CARBIDE CORPORATION (US) 1988-02-23 US claimed
US-4691069-A Hydrogentation of unsaturated aliphatic hydrocarbons SOUTH AFRICAN INVENTIONS DEVELOPMENT CORPORATION (ZA) 1987-09-01 US claimed
US-4410461-A Production of benzylic esters ASHLAND OIL, INC. (US) 1983-10-18 US claimed
US-4071568-A ACETAL WITH CARBON MONOXIDE MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JA) 1978-01-31 US claimed