Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.48 |
| ▸ | PPARG | P37231 | 3/20 | 0.48 |
| ▸ | PPARD | Q03181 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | ALPI | P09923 | 1/20 | 0.42 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17662382 | 0.86 | PPARA (0.46) | PPARAPPARGALOX15RECQLMTNR1A | |
| SCHEMBL11530015 | 0.85 | RAB9A (0.44) | PPARAALOX15RECQLMTNR1AMTNR1B | |
| SCHEMBL3102146 | 0.85 | PPARA (0.51) | PPARAPPARGPPARDL3MBTL1SSTR4 | |
| SCHEMBL7253892 | 0.80 | PPARA (0.44) | PPARAPPARGPPARDL3MBTL1 | |
| SCHEMBL5724626 | 0.79 | PPARA (0.58) | PPARAPPARGALOX15SSTR4 | |
| SCHEMBL5822085 | 0.79 | PPARA (0.44) | PPARAPPARGALOX15RECQLMTNR1A | |
| SCHEMBL7805112 | 0.78 | PPARA (0.49) | PPARAPPARGALOX15MTNR1AMTNR1B | |
| SCHEMBL5822712 | 0.77 | KDM4E (0.56) | PPARAPPARGHPGDKDM4EMEN1 | |
| SCHEMBL2517194 | 0.76 | ALDH1A1 (0.60) | PPARAPPARGALOX15MTNR1AMTNR1B | |
| SCHEMBL3465226 | 0.76 | PPARA (0.47) | PPARAPPARGALOX15MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118146110-A | N-difluoromethyl carbonyl compound and preparation method thereof | 中山大学附属第一医院 | 2024-06-07 | — | — | CN | claimed |
| CN-118146110-A | N-difluoromethyl carbonyl compound and preparation method thereof | 中山大学附属第一医院 | 2024-06-07 | — | — | CN | disclosed |
| EP-1242574-B1 | USE OF A PORTION FOR MANUAL DISHWASHING AND/OR FOR MANUAL HARD SURFACES CLEANING | HENKEL KGAA (DE) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006058199-A1 | METHODS OF MODULATING HIGH-DENSITY LIPOPROTEIN CHOLESTEROL LEVELS AND PHARMACEUTICAL FORMULATIONS FOR THE SAME | FAZIX CORPORATION (US) | 2006-06-01 | — | — | WO | disclosed |
| US-20060111346-A1 | Methods of modulating high-density lipoprotein cholesterol levels and pharmaceutical formulations for the same | FAZIX CORPORATION. | 2006-05-25 | — | — | US | disclosed |
| WO-2006021257-A1 | COLOURED, SHAPED SYNDET OR SEMI-SYNDET SOAP MATERIAL | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2006-03-02 | — | — | WO | disclosed |
| EP-1430933-A2 | Cosmetic and pharmaceutical compositions comprising steroid sulfatase inhibitors and their use for the reduction of hair loss | Henkel Kommanditgesellschaft auf Aktien (DE) | 2004-06-23 | — | — | EP | disclosed |
| EP-1117377-B1 | COSMETIC PREPARATIONS | COGNIS DEUTSCHLAND GMBH (DE) | 2004-04-21 | — | — | EP | disclosed |
| EP-1097270-B1 | USE OF PIT EMULSIONS | COGNIS DEUTSCHLAND GMBH (DE) | 2003-06-04 | — | — | EP | disclosed |
| EP-1112058-B1 | USE OF CYCLIC CARBONATES AS MOISTURISERS | COGNIS DEUTSCHLAND GMBH (DE) | 2002-11-13 | — | — | EP | disclosed |
| EP-1242574-A1 | DISHWASHER DETERGENT PORTION | Henkel Kommanditgesellschaft auf Aktien (DE) | 2002-09-25 | — | — | EP | disclosed |
| EP-1112058-A1 | USE OF CYCLIC CARBONATES AS MOISTURISERS | Cognis Deutschland GmbH (DE) | 2001-07-04 | — | — | EP | disclosed |
| EP-1097270-A1 | USE OF PIT EMULSIONS | Cognis Deutschland GmbH (DE) | 2001-05-09 | — | — | EP | disclosed |
| WO-2001029172-A1 | DISHWASHER DETERGENT PORTION | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-04-26 | — | — | WO | disclosed |
| EP-0992489-A1 | Betaines | Cognis Deutschland GmbH (DE) | 2000-04-12 | — | — | EP | disclosed |
| EP-0992488-A2 | Quaternary ammonium compounds | Henkel KGaA (DE) | 2000-04-12 | — | — | EP | disclosed |
| WO-2000015186-A1 | USE OF CYCLIC CARBONATES AS MOISTURISERS | COGNIS DEUTSCHLAND GMBH (DE) | 2000-03-23 | — | — | WO | disclosed |
| EP-0982024-A2 | Cosmetic and/or pharmaceutical W/O emulsions | Henkel KGaA (DE) | 2000-03-01 | — | — | EP | disclosed |
| WO-2000004230-A1 | USE OF PIT EMULSIONS | COGNIS DEUTSCHLAND GMBH (DE) | 2000-01-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060111346-A1 | Methods of modulating high-density lipoprotein cholesterol levels and pharmaceutical formulations for the same | HDLBP, LDLR, CETP | PPARA 194/4885PPARG 199/4885PPARD 304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.