SCHEMBL5266271

SCHEMBL5266271

[SiH3]OC(COCC1CO1)(COCC1CO1)COCC1CO1

nearest known ligand 0.57

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.57
MAPK1 P28482 1/20 0.57
ALDH1A1 P00352 6/20 0.42
SMN1; SMN2 Q16637 2/20 0.41
TDP1 Q9NUW8 2/20 0.38
TP53 P04637 4/20 0.33
CYP3A4 P08684 2/20 0.33
MAPT P10636 2/20 0.31
HPGD P15428 2/20 0.31
HIF1A Q16665 2/20 0.31
MEN1 O00255 1/20 0.31
CYP1A2 P05177 1/20 0.31
KMT2A Q03164 1/20 0.31
PPARG P37231 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8441407 0.87 TSHR (0.48) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
SCHEMBL5268219 0.79 TSHR (0.54) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
SCHEMBL4268958 0.79 TSHR (0.64) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
SCHEMBL5271678 0.77 TSHR (0.55) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
SCHEMBL614178 0.76 TSHR (0.61) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
SCHEMBL18191087 0.76 TSHR (0.59) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
SCHEMBL14329534 0.75 TSHR (0.59) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
SCHEMBL613049 0.75 TSHR (0.64) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
SCHEMBL23256373 0.74 TSHR (0.52) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
SCHEMBL1995127 0.74 SMN1; SMN2 (0.50) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0620255-B1 Antifogging abrasion resistant coating composition and synthetic resin article coated therewith LUCKY LTD (KR) 2002-02-27 EP claimed
US-5917075-A Hydrolyzable and polymerizable silanes FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG, E.V. (DE) 1999-06-29 US claimed
US-5674941-A CURABLE PROTECTIVE COATING FOR OPTICAL ARTICLES COMPRISING AN AMINE-CONTAINING SILANE AND AN ACRYLIC COPOLYMER HAVING PENDANT HYDROXY, EPOXY, AMINO AND/OR SILANE GROUPS; ANTIFOGGING AGENTS; ADHESION TO POLYCARBONATES; NONABRASIVE LUCKY LIMITED (KR) 1997-10-07 US claimed
EP-4269516-A1 COMPOSITION FOR HYBRID POLYMERS HAVING BARRIER FUNCTION Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2023-11-01 EP disclosed
EP-2714653-B1 COMPOUNDS CONTAINING (METH)ACRYLATE GROUPS AND SULFONATE OR SULFATE GROUPS, POLYMERS AND CONDENSATES MADE THEREFROM AND USE OF THE POLYMERS AND CONDENSATES FRAUNHOFER GES FORSCHUNG (DE) 2017-05-03 EP disclosed
US-9353226-B2 Compounds containing (meth)acrylate groups and sulfonate or sulfate groups, polymers and condensates made therefrom and use of the polymers and condensates Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2016-05-31 US disclosed
US-20140088279-A1 Compounds containing (meth)acrylate groups and sulfonate or sulfate groups, polymers and condensates made therefrom and use of the polymers and condensates Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2014-03-27 US disclosed
WO-2012163781-A1 COMPOUNDS CONTAINING (METH)ACRYLATE GROUPS AND SULFONATE OR SULFATE GROUPS, POLYMERS AND CONDENSATES MADE THEREFROM AND USE OF THE POLYMERS AND CONDENSATES Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2012-12-06 WO disclosed
EP-0845489-B1 Use of an agent containing polysiloxanes as antistatic agent for the production of antistatic coatings FRAUNHOFER GES FORSCHUNG (DE) 2007-10-03 EP disclosed
EP-0802218-B1 Use of a composite with an aroma or a flavours barrier layer FRAUNHOFER GES FORSCHUNG (DE) 2005-05-18 EP disclosed
US-5917075-A Hydrolyzable and polymerizable silanes FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG, E.V. (DE) 1999-06-29 US disclosed
EP-0802218-A2 Composite with an aroma or a flavours barrier layer FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 1997-10-22 EP disclosed
US-5674941-A CURABLE PROTECTIVE COATING FOR OPTICAL ARTICLES COMPRISING AN AMINE-CONTAINING SILANE AND AN ACRYLIC COPOLYMER HAVING PENDANT HYDROXY, EPOXY, AMINO AND/OR SILANE GROUPS; ANTIFOGGING AGENTS; ADHESION TO POLYCARBONATES; NONABRASIVE LUCKY LIMITED (KR) 1997-10-07 US disclosed
EP-0525392-B1 Hydrolysable and polymerisable silanes FRAUNHOFER GES FORSCHUNG (DE) 1996-08-21 EP disclosed
EP-0694550-A2 Hydrolysable and polymerisable silanes FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 1996-01-31 EP disclosed
EP-0643752-A1 RESINOUS DENTAL COMPOSITION BASED ON POLYMERISABLE POLYSILOXANES THE PROCTER & GAMBLE COMPANY (US) 1995-03-22 EP disclosed
EP-0643752-A4 RESINOUS DENTAL COMPOSITION BASED ON POLYMERISABLE POLYSILOXANES. PROCTER & GAMBLE (US) 1994-06-03 EP disclosed
WO-1993007230-A1 RESINOUS DENTAL COMPOSITION BASED ON POLYMERISABLE POLYSILOXANES THE PROCTER & GAMBLE COMPANY (US) 1993-04-15 WO disclosed
EP-0525392-A1 Hydrolysable and polymerisable silanes FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 1993-02-03 EP disclosed
US-4642266-A SCRATCH RESISTANCE AND WEATHERABILITY NIPPON SHEET GLASS CO., LTD. (JP) 1987-02-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140088279-A1 Compounds containing (meth)acrylate groups and sulfonate or sulfate groups, polymers and condensates made therefrom and use of the polymers and condensates AS3MT, TST, ALG3 TSHR 3413/4885MAPK1 2242/4885ALDH1A1 1583/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.